Human AMOT ORF/cDNA clone-Lentivirus plasmid (NM_001113490)

Cat. No.: pGMLP-SPh-035
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human AMOT/ Lentiviral expression plasmid for AMOT lentivirus packaging, AMOT lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP-SPh-035
Gene Name AMOT
Accession Number NM_001113490
Gene ID 154796
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 3255 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAGAAATTCTGAAGAACAGCCAAGTGGAGGGACCACGGTATTGCAGCGTTTGCTACAAGAGCAGCTTCGCTATGGCAATCCTAGTGAGAATCGCAGCCTGCTTGCCATACACCAGCAAGCCACAGGGAATGGCCCTCCTTTCCCCAGTGGCAGTGGGAACCCGGGCCCTCAGAGTGATGTGTTGAGTCCCCAAGACCACCACCAACAGCTTGTGGCTCATGCTGCTCGACAAGAACCCCAGGGGCAGGAAATCCAGTCAGAAAACCTCATCATGGAGAAGCAGCTGTCTCCTCGAATGCAAAATAATGAAGAACTCCCGACCTATGAAGAAGCCAAGGTCCAGTCCCAGTACTTTCGGGGCCAACAGCATGCCAGTGTTGGAGCTGCCTTCTATGTCACTGGAGTCACCAACCAGAAGATGAGGACTGAGGGACGCCCATCAGTTCAGCGGCTCAATCCTGGAAAGATGCACCAAGATGAGGGACTCAGAGACCTTAAGCAAGGGCATGTCCGTTCCTTGAGTGAACGACTAATGCAGATGTCACTGGCCACCAGTGGAGTTAAGGCCCATCCACCTGTTACCAGTGCTCCCCTCTCCCCACCACAACCCAATGACCTCTACAAGAATCCCACAAGTTCCAGTGAATTCTACAAGGCCCAAGGGCCACTTCCTAACCAGCATAGCCTGAAGGGCATGGAACACCGAGGCCCCCCACCAGAATATCCCTTCAAGGGCATGCCACCCCAATCTGTAGTGTGCAAGCCCCAAGAGCCAGGGCACTTCTATAGTGAGCATCGCCTGAACCAGCCAGGGAGAACAGAGGGGCAACTGATGAGGTATCAGCATCCCCCTGAGTATGGAGCAGCCAGGCCAGCGCAGGACATCTCATTGCCATTGTCAGCCAGGAACTCGCAGCCTCACAGCCCTACTTCTTCTCTGACCTCTGGGGGGTCCTTGCCCTTGCTACAATCTCCACCATCCACTAGATTGTCTCCTGCCCGACACCCCTTGGTCCCAAACCAGGGAGACCATTCAGCTCACCTGCCTAGGCCGCAGCAGCATTTCCTTCCTAATCAGGCTCACCAGGGGGATCATTACCGTCTCTCCCAACCTGGCCTGAGTCAGCAGCAGCAGCAACAGCAGCAGCAGCACCATCATCACCATCACCACCAACAACAGCAGCAGCAGCAGCCACAGCAGCAGCCAGGAGAAGCCTATTCAGCTATGCCTCGGGCTCAGCCATCCTCTGCTTCTTATCAGCCAGTGCCAGCAGACCCTTTTGCCATTGTTTCCAGAGCCCAGCAGATGGTTGAGATCCTCTCAGACGAGAACCGGAACTTGAGGCAAGAGTTGGAAGGATGCTATGAGAAGGTGGCAAGACTGCAGAAGGTGGAGACAGAAATCCAGCGCGTCTCGGAGGCATATGAGAACCTCGTGAAGTCATCCTCCAAAAGAGAGGCCCTAGAGAAAGCCATGAGAAACAAGCTAGAGGGCGAGATTCGGAGGATGCATGATTTCAACAGGGATCTGAGAGAGCGTCTAGAGACTGCCAACAAGCAGCTTGCAGAGAAGGAATATGAGGGGTCAGAGGACACCAGAAAAACCATCTCGCAGCTCTTTGCAAAAAATAAAGAAAGCCAGCGTGAGAAGGAGAAGCTGGAAGCGGAGCTGGCCACTGCCCGTTCTACCAATGAGGACCAAAGACGACACATCGAAATCCGAGATCAGGCCCTGAGTAATGCCCAGGCCAAGGTGGTAAAGCTGGAAGAAGAGCTGAAAAAGAAGCAAGTGTACGTTGACAAGGTGGAGAAGATGCAGCAGGCCCTTGTACAGCTCCAGGCAGCATGTGAAAAACGTGAGCAGCTAGAGCACCGTCTCCGGACACGACTGGAGAGGGAACTGGAATCCCTGAGAATCCAGCAGCGTCAGGGCAACTGTCAGCCCACCAACGTTTCAGAATACAATGCTGCTGCACTGATGGAGCTCCTTCGGGAGAAAGAGGAGAGGATTCTGGCTCTGGAAGCTGATATGACAAAGTGGGAGCAGAAATATTTGGAGGAGAATGTGATGAGACATTTTGCTCTGGATGCTGCTGCAACTGTGGCTGCTCAGAGGGACACAACAGTCATCAGTCACTCTCCTAACACCAGCTATGACACAGCTCTAGAAGCTCGCATCCAGAAAGAGGAGGAAGAAATCTTGATGGCCAATAAGCGTTGCCTTGACATGGAGGGCAGGATTAAGACCCTCCATGCCCAGATTATTGAGAAGGATGCCATGATCAAAGTACTCCAGCAGCGTTCCCGGAAGGAGCCGAGCAAGACAGAGCAGCTGTCGTGCATGCGGCCAGCGAAGTCTCTGATGTCCATTTCCAATGCTGGATCAGGCTTGCTCTCCCACTCATCCACCCTGACTGGCTCCCCCATCATGGAAGAAAAGCGAGACGACAAGAGCTGGAAGGGGAGCCTAGGCATTCTCCTGGGTGGAGACTACCGTGCTGAATATGTCCCTTCCACACCCTCGCCTGTGCCACCCTCGACTCCCCTGCTCTCGGCTCACTCCAAGACAGGCAGCCGAGACTGCAGTACCCAAACTGAACGTGGGACGGAATCGAACAAAACTGCAGCTGTTGCTCCCATCTCTGTTCCTGCTCCAGTTGCTGCTGCCGCCACTGCTGCCGCCATCACTGCCACTGCTGCCACCATCACCACCACCATGGTAGCTGCTGCTCCAGTTGCTGTTGCTGCTGCTGCTGCTCCAGCTGCTGCTGCTGCCCCGTCTCCAGCCACTGCCGCTGCTACTGCTGCTGCTGTTTCTCCAGCTGCTGCTGGTCAGATTCCAGCTGCTGCCTCTGTTGCCTCAGCTGCTGCCGTTGCTCCTTCTGCTGCTGCTGCTGCTGCTGTTCAGGTTGCTCCAGCTGCTCCGGCTCCAGTTCCAGCTCCGGCTCTGGTTCCGGTTCCAGCTCCAGCAGCGGCTCAGGCTTCTGCTCCTGCTCAGACTCAGGCACCAACTTCAGCTCCGGCTGTGGCTCCAACTCCAGCTCCAACTCCAACTCCAGCTGTGGCTCAGGCTGAGGTTCCTGCAAGTCCAGCTACCGGTCCTGGACCACATCGTTTGTCTATACCAAGTTTGACCTGCAATCCAGACAAAACAGATGGGCCTGTGTTCCACTCCAATACTCTGGAAAGAAAAACTCCCATTCAGATCCTGGGACAAGAGCCTGATGCAGAGATGGTGGAATATCTCATCTAA
ORF Protein Sequence MRNSEEQPSGGTTVLQRLLQEQLRYGNPSENRSLLAIHQQATGNGPPFPSGSGNPGPQSDVLSPQDHHQQLVAHAARQEPQGQEIQSENLIMEKQLSPRMQNNEELPTYEEAKVQSQYFRGQQHASVGAAFYVTGVTNQKMRTEGRPSVQRLNPGKMHQDEGLRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQGPLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQHPPEYGAARPAQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARHPLVPNQGDHSAHLPRPQQHFLPNQAHQGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQQQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVSRAQQMVEILSDENRNLRQELEGCYEKVARLQKVETEIQRVSEAYENLVKSSSKREALEKAMRNKLEGEIRRMHDFNRDLRERLETANKQLAEKEYEGSEDTRKTISQLFAKNKESQREKEKLEAELATARSTNEDQRRHIEIRDQALSNAQAKVVKLEEELKKKQVYVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNCQPTNVSEYNAAALMELLREKEERILALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSCMRPAKSLMSISNAGSGLLSHSSTLTGSPIMEEKRDDKSWKGSLGILLGGDYRAEYVPSTPSPVPPSTPLLSAHSKTGSRDCSTQTERGTESNKTAAVAPISVPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSIPSLTCNPDKTDGPVFHSNTLERKTPIQILGQEPDAEMVEYLI

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T47510-Ab Anti-AMOT monoclonal antibody
    Target Antigen GM-Tg-g-T47510-Ag AMOT VLP (virus-like particle)
    ORF Viral Vector pGMLV000855 Human AMOT Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-035 Human AMOT Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-175 Human AMOT Adenovirus plasmid
    ORF Viral Vector vGMLV000855 Human AMOT Lentivirus particle
    ORF Viral Vector vGMLP-SPh-035 Human AMOT Lentivirus particle
    ORF Viral Vector vGMAP-SPh-175 Human AMOT Adenovirus particle


    Target information

    Target ID GM-T47510
    Target Name AMOT
    Gene ID 154796, 27494, 707701, 300289, 101096706, 481022, 535509, 100054069
    Gene Symbol and Synonyms AMOT,CAG-2,D0Kist1,RGD1564027,Sii6
    Uniprot Accession Q4VCS5
    Uniprot Entry Name AMOT_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000126016
    Target Classification Not Available

    This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.