Human MAPK3/ERK-1/ERK1 ORF/cDNA clone-Lentivirus plasmid (NM_002746)
Cat. No.: pGMLP-SPh-054
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human MAPK3/ERK-1/ERK1 Lentiviral expression plasmid for MAPK3 lentivirus packaging, MAPK3 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.
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Product Description
Catalog ID | pGMLP-SPh-054 |
Gene Name | MAPK3 |
Accession Number | NM_002746 |
Gene ID | 5595 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 1140 bp |
Gene Alias | ERK-1,ERK1,ERT2,HS44KDAP,HUMKER1A,p44-ERK1,p44-MAPK,P44ERK1,P44MAPK,PRKM3 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTCGGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCGCGCTACACGCAGTTGCAGTACATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTATGACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCAGCCCCTTCGAACATCAGACCTACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTCATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATTGTGCAGGACCTGATGGAGACTGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAATGACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCCTCAAGTACATCCACTCCGCCAACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTTAAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTCCTGACGGAGTATGTGGCTACGCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAGGGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCATTCTGGCTGAGATGCTCTCTAACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGGCATCCTGGGCTCCCCATCCCAGGAGGACCTGAATTGTATCATCAACATGAAGGCCCGAAACTACCTACAGTCTCTGCCCTCCAAGACCAAGGTGGCTTGGGCCAAGCTTTTCCCCAAGTCAGACTCCAAAGCCCTTGACCTGCTGGACCGGATGTTAACCTTTAACCCCAATAAACGGATCACAGTGGAGGAAGCGCTGGCTCACCCCTACCTGGAGCAGTACTATGACCCGACGGATGAGCCAGTGGCCGAGGAGCCCTTCACCTTCGCCATGGAGCTGGATGACCTACCTAAGGAGCGGCTGAAGGAGCTCATCTTCCAGGAGACAGCACGCTTCCAGCCCGGAGTGCTGGAGGCCCCCTAG |
ORF Protein Sequence | MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPGVLEAP |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T23276-Ab | Anti-ERK1 monoclonal antibody |
Target Antigen | GM-Tg-g-T23276-Ag | ERK1/MAPK3 protein |
ORF Viral Vector | pGMLP005482 | Human MAPK3 Lentivirus plasmid |
ORF Viral Vector | pGMLP005593 | Human MAPK3 Lentivirus plasmid |
ORF Viral Vector | pGMLP-SPh-054 | Human MAPK3 Lentivirus plasmid |
ORF Viral Vector | pGMAP-SPh-194 | Human MAPK3 Adenovirus plasmid |
ORF Viral Vector | vGMLP005482 | Human MAPK3 Lentivirus particle |
ORF Viral Vector | vGMLP005593 | Human MAPK3 Lentivirus particle |
ORF Viral Vector | vGMLP-SPh-054 | Human MAPK3 Lentivirus particle |
ORF Viral Vector | vGMAP-SPh-194 | Human MAPK3 Adenovirus particle |
Target information
Target ID | GM-T23276 |
Target Name | ERK1 |
Gene ID | 5595, 26417, 708938, 50689, 101087958, 100855877, 531391, 100066173 |
Gene Symbol and Synonyms | ERK-1,ERK1,ERT2,Esrk1,HS44KDAP,HUMKER1A,MAPK1,MAPK3,Mnk1,Mtap2k,p44,p44-ERK1,p44-MAPK,P44ERK1,P44MAPK,PRKM3 |
Uniprot Accession | P27361 |
Uniprot Entry Name | MK03_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | IgA glomerulonephritis |
Gene Ensembl | ENSG00000102882 |
Target Classification | Kinase |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
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