Human HBEGF/DTR/DTS ORF/cDNA clone-Lentivirus plasmid (NM_001945)

Cat. No.: pGMLP000457
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HBEGF/DTR/DTS Lentiviral expression plasmid for HBEGF lentivirus packaging, HBEGF lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000457
Gene Name HBEGF
Accession Number NM_001945
Gene ID 1839
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 627 bp
Gene Alias DTR,DTS,DTSF,HEGFL
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAGCTGCTGCCGTCGGTGGTGCTGAAGCTCTTTCTGGCTGCAGTTCTCTCGGCACTGGTGACTGGCGAGAGCCTGGAGCGGCTTCGGAGAGGGCTAGCTGCTGGAACCAGCAACCCGGACCCTCCCACTGTATCCACGGACCAGCTGCTACCCCTAGGAGGCGGCCGGGACCGGAAAGTCCGTGACTTGCAAGAGGCAGATCTGGACCTTTTGAGAGTCACTTTATCCTCCAAGCCACAAGCACTGGCCACACCAAACAAGGAGGAGCACGGGAAAAGAAAGAAGAAAGGCAAGGGGCTAGGGAAGAAGAGGGACCCATGTCTTCGGAAATACAAGGACTTCTGCATCCATGGAGAATGCAAATATGTGAAGGAGCTCCGGGCTCCCTCCTGCATCTGCCACCCGGGTTACCATGGAGAGAGGTGTCATGGGCTGAGCCTCCCAGTGGAAAATCGCTTATATACCTATGACCACACAACCATCCTGGCCGTGGTGGCTGTGGTGCTGTCATCTGTCTGTCTGCTGGTCATCGTGGGGCTTCTCATGTTTAGGTACCATAGGAGAGGAGGTTATGATGTGGAAAATGAAGAGAAAGTGAAGTTGGGCATGACTAATTCCCACTGA
ORF Protein Sequence MKLLPSVVLKLFLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRKVRDLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVENRLYTYDHTTILAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDVENEEKVKLGMTNSH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T76093-Ab Anti-HBEGF/ DTR/ DTS monoclonal antibody
    Target Antigen GM-Tg-g-T76093-Ag HBEGF VLP (virus-like particle)
    ORF Viral Vector pGMLP000457 Human HBEGF Lentivirus plasmid
    ORF Viral Vector pGMAP000278 Human HBEGF Adenovirus plasmid
    ORF Viral Vector vGMLP000457 Human HBEGF Lentivirus particle
    ORF Viral Vector vGMAP000278 Human HBEGF Adenovirus particle


    Target information

    Target ID GM-T76093
    Target Name HBEGF
    Gene ID 1839, 15200, 695559, 25433, 101093578, 607007, 522921, 100629956
    Gene Symbol and Synonyms DTR,DTS,DTSF,GFHB,Hb-egf,HBEGF,HEGFL
    Uniprot Accession Q99075
    Uniprot Entry Name HBEGF_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Urinary Tract Infection, Overactive bladder
    Gene Ensembl ENSG00000113070
    Target Classification Not Available

    Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. [provided by Alliance of Genome Resources, Apr 2022]



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