Human ELA3A/ELA3 ORF/cDNA clone-Lentivirus plasmid (BC005918.1)

Cat. No.: pGMLP000753
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human ELA3A/ELA3 Lentiviral expression plasmid for ELA3A lentivirus packaging, ELA3A lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000753
Gene Name ELA3A
Accession Number BC005918.1
Gene ID 10136
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 813 bp
Gene Alias ELA3
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGATGCTCCGGCTGCTCAGTTCCCTCCTCCTTGTGGCCGTTGCCTCAGGCTATGGCCCACCTTCCTCTCACTCTTCCAGCCGCGTTGTCCATGGTGAGGATGCGGTCCCCTACAGCTGGCCCTGGCAGGTTTCCCTGCAGTATGAGAAAAGTGGAAGCTTCTACCACACGTGTGGCGGTAGCCTCACCGCCCCCGATTGGGTTGTGACTGCCGGCCACTGCATCTCGAGGGATCTGACCTACCAGGTGGTGTTGGGTGAGTACAACCTTGCTGTGAAGGAGGGCCCCGAGCAGGTGATCCCCATCAACTCTGAGGAGCTGTTTGTGCATCCACTCTGGAACCGCTCGTGTGTGGCCTGTGGCAATGACATCGCCCTCATCAAGCTCTCACGCAGCGCCCAGCTGGGAGATGCCGTCCAGCTCGCCTCACTCCCTCCCGCTGGTGACATCCTTCCCAACAAGACACCCTGCTACATCACCGGCTGGGGCCGTCTCTATACCAATGGGCCACTCCCAGACGAGCTGCAGCAGGCCCGGCTGCCCGTGGTGGACTATAAGCACTGCTCCAGGTGGAACTGGTGGGGTTCCACCGTGAAGAAAACCATGGTGTGTGCTGGAGGGTACATCCGCTCCGGCTGCAACGGTGACTCTGGAGGACCCCTCAACTGCCCCACAGAGGATGGTGGCTGGCAGGTCCACGGTGTGACCAGCTTTGTTTCTGGCTTTGGCTGCAACTTCATCTGGAAGCCCACGGTGTTCACTCGAGTCTCCGCCTTCATCGACTGGATTGAGGAGACCATAGCAAGCCACTAG
ORF Protein Sequence MMLRLLSSLLLVAVASGYGPPSSHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLTAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPLPDELQQARLPVVDYKHCSRWNWWGSTVKKTMVCAGGYIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSGFGCNFIWKPTVFTRVSAFIDWIEETIASH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0757-Ab Anti-CEL3A/ CELA3A/ ELA3 functional antibody
    Target Antigen GM-Tg-g-SE0757-Ag CELA3A protein
    ORF Viral Vector pGMLP000753 Human ELA3A Lentivirus plasmid
    ORF Viral Vector vGMLP000753 Human ELA3A Lentivirus particle


    Target information

    Target ID GM-SE0757
    Target Name CELA3A
    Gene ID 10136
    Gene Symbol and Synonyms CELA3A,ELA3,ELA3A
    Uniprot Accession P09093
    Uniprot Entry Name CEL3A_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000142789
    Target Classification Not Available

    Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. [provided by RefSeq, Jul 2008]



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