Human HMGA1/HMG-R/HMGA1A ORF/cDNA clone-Lentivirus plasmid (NM_145899)

Cat. No.: pGMLP000820
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HMGA1/HMG-R/HMGA1A Lentiviral expression plasmid for HMGA1 lentivirus packaging, HMGA1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP000820
Gene Name HMGA1
Accession Number NM_145899
Gene ID 3159
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 324 bp
Gene Alias HMG-R,HMGA1A,HMGIY
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAGTGAGTCGAGCTCGAAGTCCAGCCAGCCCTTGGCCTCCAAGCAGGAAAAGGACGGCACTGAGAAGCGGGGCCGGGGCAGGCCGCGCAAGCAGCCTCCGGTGAGTCCCGGGACAGCGCTGGTAGGGAGTCAGAAGGAGCCCAGCGAAGTGCCAACACCTAAGAGACCTCGGGGCCGACCAAAGGGAAGCAAAAACAAGGGTGCTGCCAAGACCCGGAAAACCACCACAACTCCAGGAAGGAAACCAAGGGGCAGACCCAAAAAACTGGAGAAGGAGGAAGAGGAGGGCATCTCGCAGGAGTCCTCGGAGGAGGAGCAGTGA
ORF Protein Sequence MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRPRGRPKGSKNKGAAKTRKTTTTPGRKPRGRPKKLEKEEEEGISQESSEEEQ

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T68211-Ab Anti-HMGA1 monoclonal antibody
    Target Antigen GM-Tg-g-T68211-Ag HMGA1 protein
    ORF Viral Vector pGMLP000820 Human HMGA1 Lentivirus plasmid
    ORF Viral Vector pGMPC001448 Human HMGA1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001453 Human HMGA1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000820 Human HMGA1 Lentivirus particle


    Target information

    Target ID GM-T68211
    Target Name HMGA1
    Gene ID 3159, 15361, 718536, 117062, 101094850, 442946, 618849, 100629238
    Gene Symbol and Synonyms HMG-R,HMGA1,HMGA1A,Hmga1b,Hmgi,HMGIY,Hmgy
    Uniprot Accession P17096
    Uniprot Entry Name HMGA1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000137309
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]



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