Human HBG2/HBG-T1/TNCY ORF/cDNA clone-Lentivirus plasmid (NM_000184)

Cat. No.: pGMLP000958
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HBG2/HBG-T1/TNCY Lentiviral expression plasmid for HBG2 lentivirus packaging, HBG2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000958
Gene Name HBG2
Accession Number NM_000184
Gene ID 3048
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 444 bp
Gene Alias HBG-T1,TNCY
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGTCATTTCACAGAGGAGGACAAGGCTACTATCACAAGCCTGTGGGGCAAGGTGAATGTGGAAGATGCTGGAGGAGAAACCCTGGGAAGGCTCCTGGTTGTCTACCCATGGACCCAGAGGTTCTTTGACAGCTTTGGCAACCTGTCCTCTGCCTCTGCCATCATGGGCAACCCCAAAGTCAAGGCACATGGCAAGAAGGTGCTGACTTCCTTGGGAGATGCCATAAAGCACCTGGATGATCTCAAGGGCACCTTTGCCCAGCTGAGTGAACTGCACTGTGACAAGCTGCATGTGGATCCTGAGAACTTCAAGCTCCTGGGAAATGTGCTGGTGACCGTTTTGGCAATCCATTTCGGCAAAGAATTCACCCCTGAGGTGCAGGCTTCCTGGCAGAAGATGGTGACTGGAGTGGCCAGTGCCCTGTCCTCCAGATACCACTGA
ORF Protein Sequence MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFGKEFTPEVQASWQKMVTGVASALSSRYH

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP2887-Ab Anti-HBG2 monoclonal antibody
    Target Antigen GM-Tg-g-IP2887-Ag HBG2 protein
    ORF Viral Vector pGMLP000958 Human HBG2 Lentivirus plasmid
    ORF Viral Vector vGMLP000958 Human HBG2 Lentivirus particle


    Target information

    Target ID GM-IP2887
    Target Name HBG2
    Gene ID 3048, 114672349
    Gene Symbol and Synonyms HBG-T1,HBG2,TNCY
    Uniprot Accession P69892
    Uniprot Entry Name HBG2_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease maternal health, Reduced oxygen carrying capacity
    Gene Ensembl ENSG00000196565
    Target Classification Not Available

    The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]



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