Human RHOB/ARH6/ARHB ORF/cDNA clone-Lentivirus plasmid (NM_004040)

Cat. No.: pGMLP001841
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human RHOB/ARH6/ARHB Lentiviral expression plasmid for RHOB lentivirus packaging, RHOB lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001841
Gene Name RHOB
Accession Number NM_004040
Gene ID 388
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 591 bp
Gene Alias ARH6,ARHB,MST081,MSTP081,RHOH6
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCGGCCATCCGCAAGAAGCTGGTGGTGGTGGGCGACGGCGCGTGTGGCAAGACGTGCCTGCTGATCGTGTTCAGTAAGGACGAGTTCCCCGAGGTGTACGTGCCCACCGTCTTCGAGAACTATGTGGCCGACATTGAGGTGGACGGCAAGCAGGTGGAGCTGGCGCTGTGGGACACGGCGGGCCAGGAGGACTACGACCGCCTGCGGCCGCTCTCCTACCCGGACACCGACGTCATTCTCATGTGCTTCTCGGTGGACAGCCCGGACTCGCTGGAGAACATCCCCGAGAAGTGGGTCCCCGAGGTGAAGCACTTCTGTCCCAATGTGCCCATCATCCTGGTGGCCAACAAAAAAGACCTGCGCAGCGACGAGCATGTCCGCACAGAGCTGGCCCGCATGAAGCAGGAACCCGTGCGCACGGATGACGGCCGCGCCATGGCCGTGCGCATCCAAGCCTACGACTACCTCGAGTGCTCTGCCAAGACCAAGGAAGGCGTGCGCGAGGTCTTCGAGACGGCCACGCGCGCCGCGCTGCAGAAGCGCTACGGCTCCCAGAACGGCTGCATCAACTGCTGCAAGGTGCTATGA
ORF Protein Sequence MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQKRYGSQNGCINCCKVL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T58361-Ab Anti-RHOB monoclonal antibody
    Target Antigen GM-Tg-g-T58361-Ag RHOB protein
    ORF Viral Vector pGMLP001028 Human RHOB Lentivirus plasmid
    ORF Viral Vector pGMLP001841 Human RHOB Lentivirus plasmid
    ORF Viral Vector pGMLP005661 Human RHOB Lentivirus plasmid
    ORF Viral Vector pGMPC001834 Human RHOB Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001028 Human RHOB Lentivirus particle
    ORF Viral Vector vGMLP001841 Human RHOB Lentivirus particle
    ORF Viral Vector vGMLP005661 Human RHOB Lentivirus particle


    Target information

    Target ID GM-T58361
    Target Name RHOB
    Gene ID 388, 11852, 702141, 64373, 101099371, 403670, 515118, 100056328
    Gene Symbol and Synonyms ARH6,ARHB,MST081,MSTP081,RHO,RHOB,RHOH6
    Uniprot Accession P62745
    Uniprot Entry Name RHOB_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000143878
    Target Classification Tumor-associated antigen (TAA)

    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to ionizing radiation; and regulation of cell migration. Located in cleavage furrow and endosome membrane. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Apr 2022]



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