Human C7 ORF/cDNA clone-Lentivirus plasmid (NM_000587)

Cat. No.: pGMLP002049
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human C7/ Lentiviral expression plasmid for C7 lentivirus packaging, C7 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP002049
Gene Name C7
Accession Number NM_000587
Gene ID 730
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2532 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAGGTGATAAGCTTATTCATTTTGGTGGGATTTATAGGAGAGTTCCAAAGTTTTTCAAGTGCCTCCTCTCCAGTCAACTGCCAGTGGGACTTCTATGCCCCTTGGTCAGAATGCAATGGCTGTACCAAGACTCAGACTCGCAGGCGGTCAGTTGCTGTGTATGGGCAGTATGGAGGCCAGCCTTGTGTTGGAAATGCTTTTGAAACACAGTCCTGTGAACCTACAAGAGGATGTCCAACAGAGGAGGGATGTGGAGAGCGTTTCAGGTGCTTTTCAGGTCAGTGCATCAGCAAATCATTGGTTTGCAATGGGGATTCTGACTGTGATGAAGACAGTGCTGATGAAGACAGATGTGAGGACTCAGAAAGGAGACCTTCCTGTGATATCGATAAACCTCCTCCTAACATAGAACTTACTGGAAATGGTTACAATGAACTCACTGGCCAGTTTAGGAACAGAGTCATCAATACCAAAAGTTTTGGTGGTCAATGTAGAAAGGTGTTTAGTGGGGATGGAAAAGATTTCTACAGGCTGAGTGGAAATGTCCTGTCCTATACATTCCAGGTGAAAATAAATAATGATTTTAATTATGAATTTTACAATAGTACTTGGTCTTATGTAAAACATACGTCGACAGAACACACATCATCTAGTCGGAAGCGCTCCTTTTTTAGATCTTCATCATCTTCTTCACGCAGTTATACTTCACATACCAATGAAATCCATAAAGGAAAGAGTTACCAACTGCTGGTTGTTGAGAACACTGTTGAAGTGGCTCAGTTCATTAATAACAATCCAGAATTTTTACAACTTGCTGAGCCATTCTGGAAGGAGCTTTCCCACCTCCCCTCTCTGTATGACTACAGTGCCTACCGAAGATTAATCGACCAGTACGGGACACATTATCTGCAATCTGGGTCGTTAGGAGGAGAATACAGAGTTCTATTTTATGTGGACTCAGAAAAATTAAAACAAAATGATTTTAATTCAGTCGAAGAAAAGAAATGTAAATCCTCAGGTTGGCATTTTGTCGTTAAATTTTCAAGTCATGGATGCAAGGAACTGGAAAACGCTTTAAAAGCTGCTTCAGGAACCCAGAACAATGTATTGCGAGGAGAACCGTTCATCAGAGGGGGAGGTGCAGGCTTCATATCTGGCCTTAGTTACCTAGAGCTGGACAATCCTGCTGGAAACAAAAGGCGATATTCTGCCTGGGCAGAATCTGTGACTAATCTTCCTCAAGTCATAAAACAAAAGCTGACACCTTTATATGAGCTGGTAAAGGAAGTACCTTGTGCCTCTGTGAAAAAACTATACCTGAAATGGGCTCTTGAAGAGTATCTGGATGAATTTGACCCCTGTCATTGCCGGCCTTGTCAAAATGGTGGTTTGGCTACTGTTGAGGGGACCCATTGTCTGTGCCATTGCAAACCGTACACATTTGGTGCGGCGTGTGAGCAAGGAGTCCTCGTAGGGAATCAAGCAGGAGGGGTTGATGGAGGTTGGAGTTGCTGGTCCTCTTGGAGCCCCTGTGTCCAAGGGAAGAAAACAAGAAGCCGTGAATGCAATAACCCACCTCCCAGTGGGGGTGGGAGATCCTGCGTTGGAGAAACGACAGAAAGCACACAATGCGAAGATGAGGAGCTGGAGCACTTGAGGTTGCTTGAACCACATTGCTTTCCTTTGTCTTTGGTTCCAACAGAATTCTGTCCATCACCTCCTGCCTTGAAAGATGGATTTGTTCAAGATGAAGGTACAATGTTTCCTGTGGGGAAAAATGTAGTGTACACTTGCAATGAAGGATACTCTCTTATTGGAAACCCAGTGGCCAGATGTGGAGAAGATTTACGGTGGCTTGTTGGGGAAATGCATTGTCAGAAAATTGCCTGTGTTCTACCTGTACTGATGGATGGCATACAGAGTCACCCCCAAAAACCTTTCTACACAGTTGGTGAGAAGGTGACTGTTTCCTGTTCAGGTGGCATGTCCTTAGAAGGTCCTTCAGCATTTCTCTGTGGCTCCAGCCTTAAGTGGAGTCCTGAGATGAAGAATGCCCGCTGTGTACAAAAAGAAAATCCGTTAACACAGGCAGTGCCTAAATGTCAGCGCTGGGAGAAACTGCAGAATTCAAGATGTGTTTGTAAAATGCCCTACGAATGTGGACCTTCCTTGGATGTATGTGCTCAAGATGAGAGAAGCAAAAGGATACTGCCTCTGACAGTTTGCAAGATGCATGTTCTCCACTGTCAGGGTAGAAATTACACCCTTACTGGTAGGGACAGCTGTACTCTGCCTGCCTCAGCTGAGAAAGCTTGTGGTGCCTGCCCACTGTGGGGAAAATGTGATGCTGAGAGCAGCAAATGTGTCTGCCGAGAAGCATCGGAGTGCGAGGAAGAAGGGTTTAGCATTTGTGTGGAAGTGAACGGCAAGGAGCAGACGATGTCTGAGTGTGAGGCGGGCGCTCTGAGATGCAGAGGGCAGAGCATCTCTGTCACCAGCATAAGGCCTTGTGCTGCGGAAACCCAGTAG
ORF Protein Sequence MKVISLFILVGFIGEFQSFSSASSPVNCQWDFYAPWSECNGCTKTQTRRRSVAVYGQYGGQPCVGNAFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLVCNGDSDCDEDSADEDRCEDSERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKSFGGQCRKVFSGDGKDFYRLSGNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSSSRKRSFFRSSSSSSRSYTSHTNEIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEPFWKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEEKKCKSSGWHFVVKFSSHGCKELENALKAASGTQNNVLRGEPFIRGGGAGFISGLSYLELDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALEEYLDEFDPCHCRPCQNGGLATVEGTHCLCHCKPYTFGAACEQGVLVGNQAGGVDGGWSCWSSWSPCVQGKKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPHCFPLSLVPTEFCPSPPALKDGFVQDEGTMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEMHCQKIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPEMKNARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPLTVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECEEEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2422-Ab Anti-CO7/ C7 monoclonal antibody
    Target Antigen GM-Tg-g-MP2422-Ag C7 VLP (virus-like particle)
    ORF Viral Vector pGMLP002049 Human C7 Lentivirus plasmid
    ORF Viral Vector vGMLP002049 Human C7 Lentivirus particle


    Target information

    Target ID GM-MP2422
    Target Name C7
    Gene ID 730, 109828, 696926, 117517, 101094482, 489221, 507339, 100066126
    Gene Symbol and Synonyms A530026G17,C7,Gm1238
    Uniprot Accession P10643
    Uniprot Entry Name CO7_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Prostate Cancer, kidney cancers, Diabetic Nephropathy
    Gene Ensembl ENSG00000112936
    Target Classification Not Available

    This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016]



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