Human GYPB/CD235b/GPB ORF/cDNA clone-Lentivirus plasmid (NM_002100)

Cat. No.: pGMLP002304
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human GYPB/CD235b/GPB Lentiviral expression plasmid for GYPB lentivirus packaging, GYPB lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP002304
Gene Name GYPB
Accession Number NM_002100
Gene ID 2994
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 276 bp
Gene Alias CD235b,GPB,GYP,MNS,PAS-3,SS
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTATGGAAAAATAATCTTTGTATTACTATTGTCAGAAATTGTGAGCATATCAGCATTAAGTACCACTGAGGTGGCAATGCACACTTCAACCTCTTCTTCAGTCACAAAGAGTTACATCTCATCACAGACAAATGGAGAAACGGGACAACTTGTCCATCGTTTCACTGTACCAGCTCCTGTAGTGATAATACTCATTATTTTGTGTGTGATGGCTGGTATTATTGGAACGATCCTCTTAATTTCTTACAGTATTCGCCGACTGATAAAGGCATGA
ORF Protein Sequence MYGKIIFVLLLSEIVSISALSTTEVAMHTSTSSSVTKSYISSQTNGETGQLVHRFTVPAPVVIILIILCVMAGIIGTILLISYSIRRLIKA

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0566-Ab Anti-GLPB/ GYPB/ CD235b monoclonal antibody
    Target Antigen GM-Tg-g-MP0566-Ag GYPB VLP (virus-like particle)
    ORF Viral Vector pGMLP002304 Human GYPB Lentivirus plasmid
    ORF Viral Vector vGMLP002304 Human GYPB Lentivirus particle


    Target information

    Target ID GM-MP0566
    Target Name GYPB
    Gene ID 2994
    Gene Symbol and Synonyms CD235b,GPB,GYP,GYPA,GYPB,MNS,PAS-3,SS
    Uniprot Accession P06028
    Uniprot Entry Name GLPB_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000250361
    Target Classification Not Available

    Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]



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