Human SERPINF1/EPC-1/OI12 ORF/cDNA clone-Lentivirus plasmid (NM_001329905)

Cat. No.: pGMLP002696
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SERPINF1/EPC-1/OI12 Lentiviral expression plasmid for SERPINF1 lentivirus packaging, SERPINF1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP002696
Gene Name SERPINF1
Accession Number NM_001329905
Gene ID 5176
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 696 bp
Gene Alias EPC-1,OI12,OI6,PEDF,PIG35
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAAGGGAAGCTCGCCAGGTCCACAAAGGAAATTCCCGATGAGATCAGCATTCTCCTTCTCGGTGTGGCGCACTTCAAGGGGCAGTGGGTAACAAAGTTTGACTCCAGAAAGACTTCCCTCGAGGATTTCTACTTGGATGAAGAGAGGACCGTGAGGGTCCCCATGATGTCGGACCCTAAGGCTGTTTTACGCTATGGCTTGGATTCAGATCTCAGCTGCAAGATTGCCCAGCTGCCCTTGACCGGAAGCATGAGTATCATCTTCTTCCTGCCCCTGAAAGTGACCCAGAATTTGACCTTGATAGAGGAGAGCCTCACCTCCGAGTTCATTCATGACATAGACCGAGAACTGAAGACCGTGCAGGCGGTCCTCACTGTCCCCAAGCTGAAGCTGAGTTATGAAGGCGAAGTCACCAAGTCCCTGCAGGAGATGAAGCTGCAATCCTTGTTTGATTCACCAGACTTTAGCAAGATCACAGGCAAACCCATCAAGCTGACTCAGGTGGAACACCGGGCTGGCTTTGAGTGGAACGAGGATGGGGCGGGAACCACCCCCAGCCCAGGGCTGCAGCCTGCCCACCTCACCTTCCCGCTGGACTATCACCTTAACCAGCCTTTCATCTTCGTACTGAGGGACACAGACACAGGGGCCCTTCTCTTCATTGGCAAGATTCTGGACCCCAGGGGCCCCTAA
ORF Protein Sequence MKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T54447-Ab Anti-PEDF/ SERPINF1/ EPC-1 functional antibody
    Target Antigen GM-Tg-g-T54447-Ag SERPINF1 protein
    ORF Viral Vector pGMLP002696 Human SERPINF1 Lentivirus plasmid
    ORF Viral Vector pGMLV001287 Human SERPINF1 Lentivirus plasmid
    ORF Viral Vector pGMLV001341 Human Serpinf1 Lentivirus plasmid
    ORF Viral Vector pGMAAV000386 Human SERPINF1 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMPC000744 Human SERPINF1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001020 Human SERPINF1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001028 Human SERPINF1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP002696 Human SERPINF1 Lentivirus particle
    ORF Viral Vector vGMLV001287 Human SERPINF1 Lentivirus particle
    ORF Viral Vector vGMLV001341 Human Serpinf1 Lentivirus particle
    ORF Viral Vector vGMAAV000386 Human SERPINF1 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-T54447
    Target Name SERPINF1
    Gene ID 5176, 20317, 721262, 287526, 101099915, 611276, 281386, 100072415
    Gene Symbol and Synonyms Dmrs91,EPC-1,OI12,OI6,PEDF,Pedfl,PIG35,Sdf3,SERPINF1
    Uniprot Accession P36955
    Uniprot Entry Name PEDF_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Complications of kidney transplant, Dent disease, Diabetic Nephropathy, Perinatal necrotizing enterocolitis
    Gene Ensembl ENSG00000132386
    Target Classification Not Available

    This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]



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