Human CD48/BLAST/BLAST1 ORF/cDNA clone-Lentivirus plasmid (BC016182)

Cat. No.: pGMLP003918
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CD48/BLAST/BLAST1 Lentiviral expression plasmid for CD48 lentivirus packaging, CD48 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP003918
Gene Name CD48
Accession Number BC016182
Gene ID 962
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 732 bp
Gene Alias BLAST,BLAST1,hCD48,mCD48,MEM-102,SLAMF2
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTGCTCCAGAGGTTGGGATTCGTGTCTGGCTCTGGAATTGCTACTGCTGCCTCTGTCACTCCTGGTGACCAGCATTCAAGGTCACTTGGTACATATGACCGTGGTCTCCGGCAGCAACGTGACTCTGAACATCTCTGAGAGCCTGCCTGAGAACTACAAACAACTAACCTGGTTTTATACTTTCGACCAGAAGATTGTAGAATGGGATTCCAGAAAATCTAAGTACTTTGAATCCAAATTTAAAGGCAGGGTCAGACTTGATCCTCAGAGTGGCGCACTGTACATCTCTAAGGTCCAGAAAGAGGACAACAGCACCTACATCATGAGGGTGTTGAAAAAGACTGGGAATGAGCAAGAATGGAAGATCAAGCTGCAAGTGCTTGACCCTGTACCCAAGCCTGTCATCAAAATTGAGAAGATAGAAGACATGGATGACAACTGTTATTTGAAACTGTCATGTGTGATACCTGGCGAGTCTGTAAACTACACCTGGTATGGGGACAAAAGGCCCTTCCCAAAGGAGCTCCAGAACAGTGTGCTTGAAACCACCCTTATGCCACATAATTACTCCAGGTGTTATACTTGCCAAGTCAGCAATTCTGTGAGCAGCAAGAATGGCACGGTCTGCCTCAGTCCACCCTGTACCCTGGCCCGGTCCTTTGGAGTAGAATGGATTGCAAGTTGGCTAGTGGTCACGGTGCCCACCATTCTTGGCCTGTTACTTACCTGA
ORF Protein Sequence MCSRGWDSCLALELLLLPLSLLVTSIQGHLVHMTVVSGSNVTLNISESLPENYKQLTWFYTFDQKIVEWDSRKSKYFESKFKGRVRLDPQSGALYISKVQKEDNSTYIMRVLKKTGNEQEWKIKLQVLDPVPKPVIKIEKIEDMDDNCYLKLSCVIPGESVNYTWYGDKRPFPKELQNSVLETTLMPHNYSRCYTCQVSNSVSSKNGTVCLSPPCTLARSFGVEWIASWLVVTVPTILGLLLT

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0212-Ab Anti-CD48/ BCM1/ BLAST monoclonal antibody
    Target Antigen GM-Tg-g-MP0212-Ag CD48 VLP (virus-like particle)
    ORF Viral Vector pGMLP003283 Human CD48 Lentivirus plasmid
    ORF Viral Vector pGMLP003918 Human CD48 Lentivirus plasmid
    ORF Viral Vector vGMLP003283 Human CD48 Lentivirus particle
    ORF Viral Vector vGMLP003918 Human CD48 Lentivirus particle


    Target information

    Target ID GM-MP0212
    Target Name CD48
    Gene ID 962, 12506, 719762, 245962, 101089831, 488642, 508386, 100053868
    Gene Symbol and Synonyms Bcm-1,BCM1,BLAST,BLAST-1,BLAST1,CD48,hCD48,mCD48,MEM-102,Sgp-60,SLAMF2
    Uniprot Accession P09326
    Uniprot Entry Name CD48_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000117091
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]



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