Human FCGR3B/CD16/CD16A ORF/cDNA clone-Lentivirus plasmid (NM_001244753)

Cat. No.: pGMLP004810
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human FCGR3B/CD16/CD16A Lentiviral expression plasmid for FCGR3B lentivirus packaging, FCGR3B lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP004810
Gene Name FCGR3B
Accession Number NM_001244753
Gene ID 2215
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 810 bp
Gene Alias CD16,CD16A,CD16b,FCG3,FCGR3,FCGR3A,FCR-10,FCRIII,FCRIIIb
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTGGCAGCTGCTCCTCCCAACTGCTCTGCTACTTCTAGTTTCAGCTGGCATGCGGACTGAAGATCTCCCAAAGGCTGTGGTGTTCCTGGAGCCTCAATGGTACAGCGTGCTTGAGAAGGACAGTGTGACTCTGAAGTGCCAGGGAGCCTACTCCCCTGAGGACAATTCCACACAGTGGTTTCACAATGAGAACCTCATCTCAAGCCAGGCCTCGAGCTACTTCATTGACGCTGCCACAGTCAACGACAGTGGAGAGTACAGGTGCCAGACAAACCTCTCCACCCTCAGTGACCCGGTGCAGCTAGAAGTCCATATCGGCTGGCTGTTGCTCCAGGCCCCTCGGTGGGTGTTCAAGGAGGAAGACCCTATTCACCTGAGGTGTCACAGCTGGAAGAACACTGCTCTGCATAAGGTCACATATTTACAGAATGGCAAAGACAGGAAGTATTTTCATCATAATTCTGACTTCCACATTCCAAAAGCCACACTCAAAGATAGCGGCTCCTACTTCTGCAGGGGGCTTGTTGGGAGTAAAAATGTGTCTTCAGAGACTGTGAACATCACCATCACTCAAGGTTTGGCAGTGTCAACCATCTCATCATTCTCTCCACCTGGGTACCAAGTCTCTTTCTGCTTGGTGATGGTACTCCTTTTTGCAGTGGACACAGGACTATATTTCTCTGTGAAGACAAACATTTGA
ORF Protein Sequence MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNENLISSQASSYFIDAATVNDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRKYFHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVSFCLVMVLLFAVDTGLYFSVKTNI

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-TA095-Ab Anti-FCG3B/ FCGR3B/ CD16 monoclonal antibody
    Target Antigen GM-Tg-g-TA095-Ag FCGR3B VLP (virus-like particle)
    ORF Viral Vector pGMLP004810 Human FCGR3B Lentivirus plasmid
    ORF Viral Vector vGMLP004810 Human FCGR3B Lentivirus particle


    Target information

    Target ID GM-TA095
    Target Name FCGR3B
    Gene ID 2215
    Gene Symbol and Synonyms CD16,CD16-I,CD16A,CD16b,FCG3,FCGR3,FCGR3A,FCGR3B,FCR-10,FCRIII,FCRIIIb
    Uniprot Accession O75015
    Uniprot Entry Name FCG3B_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000162747
    Target Classification Not Available

    The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]



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