Human PYY/PYY-I/PYY1 ORF/cDNA clone-Lentivirus plasmid (NM_004160)

Cat. No.: pGMLP004964
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PYY/PYY-I/PYY1 Lentiviral expression plasmid for PYY lentivirus packaging, PYY lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP004964
Gene Name PYY
Accession Number NM_004160
Gene ID 5697
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 294 bp
Gene Alias PYY-I,PYY1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGTGTTCGTGCGCAGGCCGTGGCCCGCCTTGACCACAGTGCTTCTGGCCCTGCTCGTCTGCCTAGGGGCGCTGGTCGACGCCTACCCCATCAAACCCGAGGCTCCCCGCGAAGACGCCTCGCCGGAGGAGCTGAACCGCTACTACGCCTCCCTGCGCCACTACCTCAACCTGGTCACCCGGCAGCGGTATGGGAAAAGAGACGGCCCGGACACGCTTCTTTCCAAAACGTTCTTCCCCGACGGCGAGGACCGCCCCGTCAGGTCGCGGTCGGAGGGCCCAGACCTGTGGTGA
ORF Protein Sequence MVFVRRPWPALTTVLLALLVCLGALVDAYPIKPEAPREDASPEELNRYYASLRHYLNLVTRQRYGKRDGPDTLLSKTFFPDGEDRPVRSRSEGPDLW

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T24127-Ab Anti-PYY/ PYY-I1 functional antibody
    Target Antigen GM-Tg-g-T24127-Ag PYY protein
    ORF Viral Vector pGMLP004964 Human PYY Lentivirus plasmid
    ORF Viral Vector vGMLP004964 Human PYY Lentivirus particle


    Target information

    Target ID GM-T24127
    Target Name PYY
    Gene ID 5697, 217212, 714041, 287730, 105261189, 607156, 100051539
    Gene Symbol and Synonyms GHYY,peptide-YY,PYY,PYY-I,PYY1,RATGHYY,Yy
    Uniprot Accession P10082
    Uniprot Entry Name PYY_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000131096
    Target Classification Not Available

    This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa. [provided by RefSeq, Feb 2016]



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