Human CNKSR2/CNK2/KSR2 ORF/cDNA clone-Lentivirus plasmid (NM_001168647.1)

Cat. No.: pGMLP005618
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human CNKSR2/CNK2/KSR2 Lentiviral expression plasmid for CNKSR2 lentivirus packaging, CNKSR2 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP005618
Gene Name CNKSR2
Accession Number NM_001168647.1
Gene ID 22866
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 3015 bp
Gene Alias CNK2,KSR2,MAGUIN
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCTCTGATAATGGAACCGGTGAGCAAATGGTCTCCGAGTCAAGTAGTGGACTGGATGAAAGGTCTTGATGACTGTTTGCAGCAGTATATTAAGAACTTTGAGAGGGAGAAGATCAGTGGGGACCAGCTGCTGCGCATTACACATCAGGAGCTAGAAGATCTGGGGGTCAGCCGCATTGGCCATCAGGAACTGATCTTGGAAGCAGTTGACCTTCTGTGTGCATTGAATTATGGCTTGGAAACAGAAAATCTAAAAACCCTTTCTCACAAGTTGAATGCATCTGCCAAAAATCTGCAGAATTTTATAACAGGAAGGAGAAGGAGTGGCCATTATGATGGGAGGACCAGCCGAAAATTGCCAAACGACTTTCTGACCTCAGTTGTGGATCTGATTGGAGCAGCCAAGAGTCTGCTTGCCTGGTTGGACAGGTCACCATTTGCTGCTGTGACAGACTATTCAGTTACAAGAAATAATGTCATACAACTCTGCCTGGAGTTAACAACAATTGTGCAACAGGATTGTACTGTATATGAAACAGAGAATAAAATTCTTCACGTGTGTAAAACTCTTTCTGGAGTCTGTGACCACATCATATCCCTGTCGTCAGATCCTCTGGTTTCACAGTCTGCTCACCTGGAAGTGATTCAACTGGCAAACATTAAACCAAGCGAAGGGCTGGGTATGTATATTAAATCTACATATGATGGCCTCCATGTAATTACTGGAACCACAGAAAATTCACCTGCAGATCGGTGCAAGAAAATCCATGCTGGCGATGAAGTGATTCAAGTTAATCATCAGACTGTGGTGGGGTGGCAGTTGAAAAATTTGGTGAATGCACTACGAGAGGACCCGAGTGGTGTTATCTTAACTTTGAAAAAGCGACCTCAGAGCATGCTTACCTCAGCACCAGCTTTACTGAAAAATATGAGATGGAAGCCCCTTGCTCTGCAGCCTCTTATACCTAGAAGTCCCACAAGCAGCGTTGCCACGCCTTCCAGCACCATCAGTACACCCACCAAAAGAGACAGTTCTGCCCTCCAGGATCTCTACATTCCCCCTCCTCCTGCAGAACCATATATTCCCAGGGATGAAAAAGGAAACCTTCCTTGTGAAGACCTCAGAGGACATATGGTGGGCAAGCCAGTGCATAAGGGATCTGAATCACCAAATTCATTTCTGGATCAGGAATATCGAAAGAGATTTAATATTGTCGAAGAAGATACTGTCTTATATTGCTATGAATATGAAAAAGGAAGATCAAGTAGTCAAGGAAGACGAGAAAGCACCCCAACTTATGAAAACTCTCTACTTCGGTATATGAGCAATGAAAAGATTGCTCAAGAAGAATACATGTTTCAGAGAAACAGCAAAAAGGACACAGGGAAGAAGTCAAAAAAGAAGGGTGATAAGAGTAATAGCCCAACTCACTATTCATTGCTACCTAGTTTACAAATGGATGCACTGAGACAAGACATCATGGGCACTCCTGTGCCAGAGACCACACTATACCATACATTTCAGCAGTCCTCACTGCAGCACAAATCAAAGAAGAAAAACAAAGGTCCTATAGCAGGCAAGAGCAAAAGACGAATTTCTTGCAAAGATCTTGGCCGTGGTGACTGTGAGGGCTGGCTTTGGAAAAAGAAAGATGCGAAGAGTTACTTTTCACAGAAATGGAAAAAATATTGGTTTGTCCTAAAGGATGCATCCCTTTATTGGTATATTAATGAGGAGGATGAAAAAGCAGAAGGATTCATTAGCCTGCCTGAATTTAAAATTGATAGAGCCAGTGAATGCCGCAAAAAATATGCATTCAAAGCCTGTCATCCTAAAATCAAAAGCTTTTATTTTGCTGCTGAACATCTTGATGATATGAACAGGTGGCTTAACAGAATTAATATGCTGACTGCAGGATATGCAGAAAGAGAGAGGATTAAGCAGGAACAAGATTACTGGAGTGAGAGTGACAAGGAAGAAGCAGATACTCCATCAACACCAAAACAAGATAGCCCTCCACCCCCATATGATACATACCCACGACCTCCCTCGATGAGTTGCGCCAGTCCTTATGTGGAAGCAAAACATAGCCGACTTTCCTCCACGGAGACTTCTCAGTCTCAGTCTTCTCATGAGGAGTTTCGCCAGGAAGTAACTGGGAGCAGTGCAGTGTCTCCCATTCGCAAGACAGCCAGTCAGCGCCGCTCCTGGCAGGATTTAATTGAGACGCCACTGACAAGTTCAGGCTTACACTATCTTCAGACTCTGCCCCTGGAGGATTCTGTCTTCTCTGACTCCGCGGCCATCTCCCCAGAGCACAGGCGGCAGTCTACCCTGCCAACTCAGAAATGCCACCTGCAGGATCACTATGGGCCATACCCCTTAGCTGAGAGTGAGAGGATGCAAGTGCTAAATGGAAATGGGGGCAAGCCTCGAAGTTTTACTCTGCCTCGAGATAGCGGGTTCAACCATTGCTGTCTGAATGCTCCAGTTAGTGCCTGTGACCCACAGGATGACGTGCAACCCCCAGAGGTGGAGGAAGAGGAGGAGGAGGAGGAGGAGGAAGGGGAGGCAGCAGGGGAAAACATAGGAGAAAAAAGTGAAAGCAGAGAAGAAAAGTTAGGAGACTCATTGCAAGATTTATACAGGGCACTGGAGCAGGCCAGTCTGTCACCACTAGGAGAACATCGTATTTCAACCAAGATGGAATACAAGCTATCATTTATAAAAAGATGTAATGATCCTGTAATGAATGAAAAACTACACCGGCTGAGAATTCTCAAAAGCACTTTAAAGGCCAGAGAAGGGGAAGTAGCCATTATCGATAAAGTCCTAGACAATCCAGACTTGACATCTAAAGAATTCCAACAATGGAAGCAGATGTACCTCGACCTTTTCTTGGATATCTGTCAAAATACCACCTCAAATGACCCACTGAGTATTTCTTCTGAAGTAGATGTAATCACTTCCTCTCTAGCACACACTCATTCATACATTGAAACGCATGTCTAA
ORF Protein Sequence MALIMEPVSKWSPSQVVDWMKGLDDCLQQYIKNFEREKISGDQLLRITHQELEDLGVSRIGHQELILEAVDLLCALNYGLETENLKTLSHKLNASAKNLQNFITGRRRSGHYDGRTSRKLPNDFLTSVVDLIGAAKSLLAWLDRSPFAAVTDYSVTRNNVIQLCLELTTIVQQDCTVYETENKILHVCKTLSGVCDHIISLSSDPLVSQSAHLEVIQLANIKPSEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALREDPSGVILTLKKRPQSMLTSAPALLKNMRWKPLALQPLIPRSPTSSVATPSSTISTPTKRDSSALQDLYIPPPPAEPYIPRDEKGNLPCEDLRGHMVGKPVHKGSESPNSFLDQEYRKRFNIVEEDTVLYCYEYEKGRSSSQGRRESTPTYENSLLRYMSNEKIAQEEYMFQRNSKKDTGKKSKKKGDKSNSPTHYSLLPSLQMDALRQDIMGTPVPETTLYHTFQQSSLQHKSKKKNKGPIAGKSKRRISCKDLGRGDCEGWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKAEGFISLPEFKIDRASECRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRINMLTAGYAERERIKQEQDYWSESDKEEADTPSTPKQDSPPPPYDTYPRPPSMSCASPYVEAKHSRLSSTETSQSQSSHEEFRQEVTGSSAVSPIRKTASQRRSWQDLIETPLTSSGLHYLQTLPLEDSVFSDSAAISPEHRRQSTLPTQKCHLQDHYGPYPLAESERMQVLNGNGGKPRSFTLPRDSGFNHCCLNAPVSACDPQDDVQPPEVEEEEEEEEEEGEAAGENIGEKSESREEKLGDSLQDLYRALEQASLSPLGEHRISTKMEYKLSFIKRCNDPVMNEKLHRLRILKSTLKAREGEVAIIDKVLDNPDLTSKEFQQWKQMYLDLFLDICQNTTSNDPLSISSEVDVITSSLAHTHSYIETHV

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2059-Ab Anti-CNKR2/ CNKSR2/ CNK2 monoclonal antibody
    Target Antigen GM-Tg-g-MP2059-Ag CNKSR2 VLP (virus-like particle)
    ORF Viral Vector pGMLP005618 Human CNKSR2 Lentivirus plasmid
    ORF Viral Vector vGMLP005618 Human CNKSR2 Lentivirus particle


    Target information

    Target ID GM-MP2059
    Target Name CNKSR2
    Gene ID 22866, 245684, 696046, 59322, 101083322, 119868389, 534112, 100059301
    Gene Symbol and Synonyms CNK2,CNKSR2,KSR2,MAGUIN,MRXSHG
    Uniprot Accession Q8WXI2
    Uniprot Entry Name CNKR2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000149970
    Target Classification Not Available

    This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]



    About GMVC

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