Human RNF43/RNF124/ SSPCS ORF/cDNA clone-Lentivirus plasmid (NM_017763.4)

Pre-made Human RNF43/RNF124/ SSPCS Lentiviral expression plasmid for RNF43 lentivirus packaging, RNF43 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to RNF43/RNF124 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000103 Human RNF43 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMLV000103
Gene Name RNF43
Accession Number NM_017763.4
Gene ID 54894
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2352 bp
Gene Alias RNF124, SSPCS, URCC
Fluorescent Reporter Luciferase
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T45968-Ab Anti-RNF43/ RNF124/ SSPCS monoclonal antibody
    Target Antigen GM-Tg-g-T45968-Ag RNF43 VLP (virus-like particle)
    ORF Viral Vector pGMLV000103 Human RNF43 Lentivirus plasmid
    ORF Viral Vector pGMLV000560 Human RNF43 Lentivirus plasmid
    ORF Viral Vector vGMLV000103 Human RNF43 Lentivirus particle
    ORF Viral Vector vGMLV000560 Human RNF43 Lentivirus particle


    Target information

    Target ID GM-T45968
    Target Name RNF43
    Gene ID 54894, 207742, 710124, 303412, 101097109, 491114, 784035, 100057001
    Gene Symbol and Synonyms 4732452J19Rik,RGD1305204,RNF124,RNF43,SSPCS,URCC
    Uniprot Accession Q68DV7
    Uniprot Entry Name RNF43_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000108375
    Target Classification Not Available

    The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.