Human RASGRP1/CALDAG-GEFI/ CALDAG-GEFII ORF/cDNA clone-Lentivirus plasmid (NM_005739)

Pre-made Human RASGRP1/CALDAG-GEFI/ CALDAG-GEFII Lentiviral expression plasmid for RASGRP1 lentivirus packaging, RASGRP1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to RASGRP1/CALDAG-GEFI products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000208 Human RASGRP1 Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMLV000208
Gene Name RASGRP1
Accession Number NM_005739
Gene ID 10125
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2394 bp
Gene Alias CALDAG-GEFI, CALDAG-GEFII, IMD64, RASGRP
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag Null
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2286-Ab Anti-GRP1/ RASGRP1/ CALDAG-GEFI monoclonal antibody
    Target Antigen GM-Tg-g-MP2286-Ag RASGRP1 VLP (virus-like particle)
    ORF Viral Vector pGMLV000208 Human RASGRP1 Lentivirus plasmid
    ORF Viral Vector pGMPC000881 Human RASGRP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV000208 Human RASGRP1 Lentivirus particle


    Target information

    Target ID GM-MP2286
    Target Name RASGRP1
    Gene ID 10125, 19419, 703838, 29434, 101093110, 478255, 533125, 100071578
    Gene Symbol and Synonyms CALDAG-GEFI,CALDAG-GEFII,IMD64,RASGRP,RASGRP1
    Uniprot Accession O95267
    Uniprot Entry Name GRP1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000172575
    Target Classification Not Available

    This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.