Human CYP19A1/ARO/ ARO1 ORF/cDNA clone-Lentivirus plasmid (NM_000103.3)
Pre-made Human CYP19A1/ARO/ ARO1 Lentiviral expression plasmid for CYP19A1 lentivirus packaging, CYP19A1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMLV000457 | Human CYP19A1 Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMLV000457 |
Gene Name | CYP19A1 |
Accession Number | NM_000103.3 |
Gene ID | 1588 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 1512 bp |
Gene Alias | ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocinmyocin |
Fusion Tag | Null |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T13260-Ab | Anti-CYP19A1 monoclonal antibody |
Target Antigen | GM-Tg-g-T13260-Ag | CYP19A1 protein |
ORF Viral Vector | pGMLV000457 | Human CYP19A1 Lentivirus plasmid |
ORF Viral Vector | pGMAAV001256 | Human CYP19A1 Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | pGMAP000276 | Human CYP19A1 Adenovirus plasmid |
ORF Viral Vector | vGMLV000457 | Human CYP19A1 Lentivirus particle |
ORF Viral Vector | vGMAAV001256 | Human CYP19A1 Adeno-associate virus(AAV) particle |
ORF Viral Vector | vGMAP000276 | Human CYP19A1 Adenovirus particle |
Target information
Target ID | GM-T13260 |
Target Name | CYP19A1 |
Gene ID | 1588, 13075, 678697, 25147, 101094932, 494003, 281740, 100009712 |
Gene Symbol and Synonyms | Ar,ArKO,ARO,ARO1,Aromatase,CPV1,CYAR,CYP19,Cyp19a,CYP19A1,CYP19P1,CYPXIX,Int-5,Int5,P-450AROM,p450arom |
Uniprot Accession | P11511 |
Uniprot Entry Name | CP19A_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Breast cancer |
Gene Ensembl | ENSG00000137869 |
Target Classification | Not Available |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.