Human AR/AIS/ AR8 ORF/cDNA clone-Lentivirus plasmid (NM_000044)

Pre-made Human AR/AIS/ AR8 Lentiviral expression plasmid for AR lentivirus packaging, AR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

Target products collectionGo to AR/AIS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMLV000461 Human AR Lentivirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug

Product Description

Catalog ID pGMLV000461
Gene Name AR
Accession Number NM_000044
Gene ID 367
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 2763 bp
Fluorescent Reporter
Mammalian Cell Selection Puromyocinmyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin


    Data / case study

    Click to get more Data / Case study about the product.

    Associated products

    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T11211-Ab Anti-AR monoclonal antibody
    Target Antigen GM-Tg-g-T11211-Ag AR protein
    ORF Viral Vector pGMLV000461 Human AR Lentivirus plasmid
    ORF Viral Vector pGMLV000610 Rat Ar Lentivirus plasmid
    ORF Viral Vector pGMLV001981 Human AR Lentivirus plasmid
    ORF Viral Vector pGMLV001990 Human AR Lentivirus plasmid
    ORF Viral Vector vGMLV000461 Human AR Lentivirus particle
    ORF Viral Vector vGMLV000610 Rat Ar Lentivirus particle
    ORF Viral Vector vGMLV001981 Human AR Lentivirus particle
    ORF Viral Vector vGMLV001990 Human AR Lentivirus particle

    Target information

    Target ID GM-T11211
    Target Name AR
    Gene ID 367, 11835, 574293, 24208, 101081787, 403588, 280675, 100033980
    Gene Symbol and Synonyms AIS,Andr,AR,AR8,DHTR,HUMARA,HYSP1,KD,NR3C4,SBMA,SMAX1,TFM
    Uniprot Accession P10275
    Uniprot Entry Name ANDR_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target, Immuno-oncology Target
    Disease Prostatic neoplasms, Prostate cancer
    Gene Ensembl ENSG00000169083
    Target Classification Checkpoint-Immuno Oncology, Nuclear Receptors

    The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]

    About GMVC


    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.