Human DUSP1/CL100/HVH1 ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_004417.4)

Cat. No.: pGMPC000141
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DUSP1/CL100/HVH1 Non-Viral expression plasmid (overexpression vector) for mouse DUSP1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC000141
Gene Name DUSP1
Accession Number NM_004417.4
Gene ID 1843
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1104 bp
Gene Alias CL100,HVH1,MKP-1,MKP1,PTPN10
Fluorescent Reporter null
Mammalian Cell Selection Neomycin
Fusion Tag MYC (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGTCATGGAAGTGGGCACCCTGGACGCTGGAGGCCTGCGGGCGCTGCTGGGGGAGCGAGCGGCGCAATGCCTGCTGCTGGACTGCCGCTCCTTCTTCGCTTTCAACGCCGGCCACATCGCCGGCTCTGTCAACGTGCGCTTCAGCACCATCGTGCGGCGCCGGGCCAAGGGCGCCATGGGCCTGGAGCACATCGTGCCCAACGCCGAGCTCCGCGGCCGCCTGCTGGCCGGCGCCTACCACGCCGTGGTGTTGCTGGACGAGCGCAGCGCCGCCCTGGACGGCGCCAAGCGCGACGGCACCCTGGCCCTGGCGGCCGGCGCGCTCTGCCGCGAGGCGCGCGCCGCGCAAGTCTTCTTCCTCAAAGGAGGATACGAAGCGTTTTCGGCTTCCTGCCCGGAGCTGTGCAGCAAACAGTCGACCCCCATGGGGCTCAGCCTTCCCCTGAGTACTAGCGTCCCTGACAGCGCGGAATCTGGGTGCAGTTCCTGCAGTACCCCACTCTACGATCAGGGTGGCCCGGTGGAAATCCTGCCCTTTCTGTACCTGGGCAGTGCGTATCACGCTTCCCGCAAGGACATGCTGGATGCCTTGGGCATCACTGCCTTGATCAACGTCTCAGCCAATTGTCCCAACCATTTTGAGGGTCACTACCAGTACAAGAGCATCCCTGTGGAGGACAACCACAAGGCAGACATCAGCTCCTGGTTCAACGAGGCCATTGACTTCATAGACTCCATCAAGAATGCTGGAGGAAGGGTGTTTGTCCACTGCCAGGCAGGCATTTCCCGGTCAGCCACCATCTGCCTTGCTTACCTTATGAGGACTAATCGAGTCAAGCTGGACGAGGCCTTTGAGTTTGTGAAGCAGAGGCGAAGCATCATCTCTCCCAACTTCAGCTTCATGGGCCAGCTGCTGCAGTTTGAGTCCCAGGTGCTGGCTCCGCACTGTTCGGCAGAGGCTGGGAGCCCCGCCATGGCTGTGCTCGACCGAGGCACCTCCACCACCACCGTGTTCAACTTCCCCGTCTCCATCCCTGTCCACTCCACGAACAGTGCGCTGAGCTACCTTCAGAGCCCCATTACGACCTCTCCCAGCTGCTGA
ORF Protein Sequence MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T35194-Ab Anti-DUSP1 monoclonal antibody
    Target Antigen GM-Tg-g-T35194-Ag DUSP1 protein
    ORF Viral Vector pGMLP005620 Human DUSP1 Lentivirus plasmid
    ORF Viral Vector pGMLV002632 Human DUSP1 Lentivirus plasmid
    ORF Viral Vector pGMPC000141 Human DUSP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000353 Human DUSP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004779 Human DUSP1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP005620 Human DUSP1 Lentivirus particle
    ORF Viral Vector vGMLV002632 Human DUSP1 Lentivirus particle


    Target information

    Target ID GM-T35194
    Target Name DUSP1
    Gene ID 1843, 19252, 702981, 114856, 101093416, 489117, 539175, 100069834
    Gene Symbol and Synonyms 3CH134,CL100,DUSP1,erp,HVH1,MKP-1,MKP1,PTPN10,Ptpn16
    Uniprot Accession P28562
    Uniprot Entry Name DUS1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000120129
    Target Classification Tumor-associated antigen (TAA)

    The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]



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