Human SQSTM1/A170/DMRV ORF/cDNA clone-Mammalian (Non-Viral Vector) plasmid (NM_003900.5)

Cat. No.: pGMPC004863
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SQSTM1/A170/DMRV Non-Viral expression plasmid (overexpression vector) for mouse SQSTM1 overexpression in unique cell transient transfection and stable cell line development.

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Product Description

Catalog ID pGMPC004863
Gene Name SQSTM1
Accession Number NM_003900.5
Gene ID 8878
Species Human
Product Type Mammalian (Non-Viral Vector) plasmid (overexpression)
Insert Length 1323 bp
Gene Alias A170,DMRV,FTDALS3,NADGP,OSIL,p60,p62,p62B,PDB3,ZIP3
Fluorescent Reporter Null
Mammalian Cell Selection Puromyocin
Fusion Tag HA (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCGTCGCTCACCGTGAAGGCCTACCTTCTGGGCAAGGAGGACGCGGCGCGCGAGATTCGCCGCTTCAGCTTCTGCTGCAGCCCCGAGCCTGAGGCGGAAGCCGAGGCTGCGGCGGGTCCGGGACCCTGCGAGCGGCTGCTGAGCCGGGTGGCCGCCCTGTTCCCCGCGCTGCGGCCTGGCGGCTTCCAGGCGCACTACCGCGATGAGGACGGGGACTTGGTTGCCTTTTCCAGTGACGAGGAATTGACAATGGCCATGTCCTACGTGAAGGATGACATCTTCCGAATCTACATTAAAGAGAAAAAAGAGTGCCGGCGGGACCACCGCCCACCGTGTGCTCAGGAGGCGCCCCGCAACATGGTGCACCCCAATGTGATCTGCGATGGCTGCAATGGGCCTGTGGTAGGAACCCGCTACAAGTGCAGCGTCTGCCCAGACTACGACTTGTGTAGCGTCTGCGAGGGAAAGGGCTTGCACCGGGGGCACACCAAGCTCGCATTCCCCAGCCCCTTCGGGCACCTGTCTGAGGGCTTCTCGCACAGCCGCTGGCTCCGGAAGGTGAAACACGGACACTTCGGGTGGCCAGGATGGGAAATGGGTCCACCAGGAAACTGGAGCCCACGTCCTCCTCGTGCAGGGGAGGCCCGCCCTGGCCCCACGGCAGAATCAGCTTCTGGTCCATCGGAGGATCCGAGTGTGAATTTCCTGAAGAACGTTGGGGAGAGTGTGGCAGCTGCCCTTAGCCCTCTGGGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGA
ORF Protein Sequence MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T17367-Ab Anti-SQSTM1 monoclonal antibody
    Target Antigen GM-Tg-g-T17367-Ag SQSTM1 protein
    ORF Viral Vector pGMLP001154 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMLP003899 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMLV000807 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMLV000821 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMAP000095 Human SQSTM1 Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-114 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-254 Human SQSTM1 Adenovirus plasmid
    ORF Viral Vector pGMPC001112 Human SQSTM1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001423 Human SQSTM1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004863 Human SQSTM1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001154 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMLP003899 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMLV000807 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMLV000821 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMAP000095 Human SQSTM1 Adenovirus particle
    ORF Viral Vector vGMLP-SPh-114 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-254 Human SQSTM1 Adenovirus particle


    Target information

    Target ID GM-T17367
    Target Name SQSTM1
    Gene ID 8878, 18412, 705481, 113894, 101085431, 481459, 338045, 100067231
    Gene Symbol and Synonyms A170,DMRV,FTDALS3,NADGP,OSF-6,Osi,OSIL,p60,p62,p62B,PDB3,SQSTM1,STAP,STONE14,ZIP,ZIP3
    Uniprot Accession Q13501
    Uniprot Entry Name SQSTM_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000161011
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]



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