Human SQSTM1/p60/p62 ORF/cDNA clone-Adenovirus particle (BC003139)

Cat. No.: vGMAP000095

Pre-made Human SQSTM1/p60/p62 Adenovirus for SQSTM1 overexpression in-vitro and in-vivo. The SQSTM1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified SQSTM1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAP000095 Human SQSTM1 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAP000095
Gene Name SQSTM1
Accession Number BC003139
Gene ID 8878
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length bp
Gene Alias p60,p62,ZIP3
Fluorescent Reporter GFP
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Kanamycin
ORF Nucleotide Sequence ATGGCGTCGCTCACCGTGAAGGCCTACCTTCTGGGCAAGGAGGACGCGGCGCGCGAGATTCGCCGCTTCAGCTTCTGCTGCAGCCCCGAGCCTGAGGCGGAAGCCGAGGCTGCGGCGGGTCCGGGACCCTGCGAGCGGCTGCTGAGCCGGGTGGCCGCCCTGTTCCCCGCGCTGCGGCCTGGCGGCTTCCAGGCGCACTACCGCGATGAGGACGGGGACTTGGTTGCCTTTTCCAGTGACGAGGAATTGACAATGGCCATGTCCTACGTGAAGGATGACATCTTCCGAATCTACATTAAAGAGAAAAAAGAGTGCCGGCGGGACCACCGCCCACCGTGTGCTCAGGAGGCGCCCCGCAACATGGTGCACCCCAATGTGATCTGCGATGGCTGCAATGGGCCTGTGGTAGGAACCCGCTACAAGTGCAGCGTCTGCCCAGACTACGACTTGTGTAGCGTCTGCGAGGGAAAGGGCTTGCACCGGGGGCACACCAAGCTCGCATTCCCCAGCCCCTTCGGGCACCTGTCTGAGGGCTTCTCGCACAGCCGCTGGCTCCGGAAGGTGAAACACGGACACTTCGGGTGGCCAGGATGGGAAATGGGTCCACCAGGAAACTGGAGCCCACGTCCTCCTCGTGCAGGGGAGGCCCGCCCTGGCCCCACGGCAGAATCAGCTTCTGGTCCATCGGAGGATCCGAGTGTGAATTTCCTGAAGAACGTTGGGGAGAGTGTGGCAGCTGCCCTTAGCCCTCTGGGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGATCCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATGAGAAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGA
ORF Protein Sequence MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T17367-Ab Anti-SQSTM1 monoclonal antibody
    Target Antigen GM-Tg-g-T17367-Ag SQSTM1 protein
    ORF Viral Vector pGMLP001154 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMLP003899 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMLV000807 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMLV000821 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMAP000095 Human SQSTM1 Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-114 Human SQSTM1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-254 Human SQSTM1 Adenovirus plasmid
    ORF Viral Vector pGMPC001112 Human SQSTM1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC001423 Human SQSTM1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC004863 Human SQSTM1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP001154 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMLP003899 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMLV000807 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMLV000821 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMAP000095 Human SQSTM1 Adenovirus particle
    ORF Viral Vector vGMLP-SPh-114 Human SQSTM1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-254 Human SQSTM1 Adenovirus particle


    Target information

    Target ID GM-T17367
    Target Name SQSTM1
    Gene ID 8878, 18412, 705481, 113894, 101085431, 481459, 338045, 100067231
    Gene Symbol and Synonyms A170,DMRV,FTDALS3,NADGP,OSF-6,Osi,OSIL,p60,p62,p62B,PDB3,SQSTM1,STAP,STONE14,ZIP,ZIP3
    Uniprot Accession Q13501
    Uniprot Entry Name SQSTM_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000161011
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.