Human CEMIP2/TMEM2 ORF/cDNA clone-Adenovirus particle (NM_013390.3)

Cat. No.: vGMAD001035

Pre-made Human CEMIP2/TMEM2 Adenovirus for CEMIP2 overexpression in-vitro and in-vivo. The CEMIP2 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified CEMIP2-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD001035 Human CEMIP2 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD001035
Gene Name CEMIP2
Accession Number NM_013390.3
Gene ID 23670
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 4152 bp
Gene Alias TMEM2
Fluorescent Reporter Firefly luciferase
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter EF1
Resistance Kanamycin
ORF Nucleotide Sequence ATGTATGCCACTGATTCCAGGGGACACTCCCCTGCTTTCCTCCAACCTCAGAATGGAAATAGTCGTCACCCATCTGGCTATGTTCCAGGGAAGGTTGTCCCATTGCGTCCCCCTCCTCCTCCAAAGAGTCAAGCTTCAGCCAAATTTACCTCCATCAGACGAGAAGACCGGGCAACCTTCGCATTCTCACCTGAAGAACAGCAAGCCCAGAGAGAAAGTCAAAAGCAAAAGAGACACAAAAATACTTTCATTTGTTTTGCTATTACTAGTTTCTCATTTTTTATTGCACTTGCAATCATTTTAGGAATATCCTCAAAATATGCTCCAGATGAAAATTGCCCAGATCAAAATCCTCGTCTCAGGAATTGGGATCCAGGACAAGATTCTGCAAAGCAAGTTGTTATCAAGGAGGGAGATATGCTCCGTCTGACCTCAGACGCCACCGTGCATTCTATAGTCATTCAGGATGGAGGACTGCTTGTATTTGGGGACAATAAAGATGGATCCAGAAATATTACTTTGAGGACTCATTACATCCTGATCCAGGATGGTGGGGCGCTTCATATTGGAGCAGAAAAATGCCGCTATAAATCCAAAGCGACAATTACCTTGTATGGCAAGTCAGATGAAGGTGAAAGTATGCCAACATTTGGCAAAAAGTTTATTGGTGTGGAAGCTGGCGGGACACTGGAGTTACATGGGGCACGGAAGGCATCGTGGACGTTGTTGGCAAGGACCCTGAATTCCTCAGGCTTGCCCTTTGGGTCCTATACCTTTGAAAAGGACTTTTCCCGGGGCCTCAATGTGAGGGTCATTGACCAAGACACGGCCAAAATTTTGGAAAGTGAGAGATTTGATACCCATGAATACCGCAATGAGAGCAGGCGGCTTCAGGAGTTTCTGAGATTCCAGGATCCAGGTCGGATTGTTGCCATAGCTGTCGGGGATTCAGCCGCTAAAAGTCTCTTACAAGGAACCATCCAGATGATCCAGGAACGGTTGGGAAGTGAACTGATCCAAGGACTGGGCTACAGGCAAGCTTGGGCTTTAGTTGGTGTCATTGATGGTGGAAGCACTTCTTGCAATGAATCCGTGAGAAACTATGAAAATCATAGCAGTGGCGGGAAGGCTCTTGCCCAAAGAGAATTTTATACTGTGGATGGCCAGAAGTTCTCTGTGACAGCTTATAGTGAATGGATTGAAGGCGTTTCTCTTTCAGGATTCCGGGTAGAGGTTGTAGATGGAGTGAAGCTAAATTTGCTAGATGATGTTAGTAGTTGGAAACCTGGAGACCAGATTGTGGTCGCAAGCACAGACTATTCCATGTACCAAGCAGAGGAGTTCACTCTTCTTCCCTGTTCTGAATGCAGCCATTTTCAGGTCAAAGTCAAAGAAACCCCTCAGTTCCTGCACATGGGTGAGATCATAGACGGTGTAGACATGAGAGCTGAGGTTGGAATTCTTACCCGGAATATTGTGATCCAAGGAGAAGTGGAGGACTCATGCTACGCAGAAAATCAGTGCCAATTTTTTGATTATGATACCTTTGGGGGACACATTATGATAATGAAAAATTTTACTTCAGTCCATCTTTCTTATGTGGAATTGAAACACATGGGTCAGCAGCAGATGGGGCGATACCCTGTTCATTTTCACCTGTGTGGTGACGTGGATTATAAAGGAGGATACAGACATGCAACATTTGTGGACGGCCTGTCTATTCATCACAGCTTCTCAAGGTGCATCACTGTGCATGGGACAAATGGCTTGCTAATAAAAGACACCATTGGGTTTGACACACTAGGTCATTGTTTCTTTTTGGAAGATGGTATTGAACAGAGGAATACTTTGTTCCACAATCTGGGACTCCTCACCAAGCCGGGTACTCTCCTGCCCACCGATAGGAACAACTCCATGTGTACCACCATGCGAGATAAAGTGTTTGGAAATTACATTCCTGTGCCTGCTACTGACTGTATGGCTGTTTCAACTTTCTGGATTGCTCATCCCAACAATAATCTGATTAATAATGCAGCTGCAGGCTCACAGGATGCTGGAATATGGTATTTATTCCACAAGGAACCAACTGGGGAATCCAGTGGATTGCAGCTCTTGGCAAAACCAGAACTCACTCCATTGGGTATATTTTATAACAACAGGGTCCATTCAAATTTTAAGGCTGGCTTATTTATTGACAAAGGTGTCAAAACAACCAACTCTAGTGCTGCTGACCCAAGGGAATACCTCTGTTTGGACAATAGTGCAAGATTTCGACCTCATCAGGATGCAAACCCCGAAAAACCACGTGTTGCTGCTCTAATTGACAGGCTCATTGCTTTTAAAAATAATGATAATGGAGCTTGGGTCAGAGGAGGAGATATTATCGTTCAAAATTCAGCATTTGCAGATAATGGAATAGGACTGACCTTTGCCAGTGATGGAAGCTTCCCAAGTGATGAAGGTTCCAGCCAAGAGGTATCTGAATCTCTCTTTGTTGGGGAGAGCAGGAATTACGGCTTTCAGGGTGGTCAGAACAAGTATGTAGGCACTGGAGGAATAGACCAGAAGCCTCGAACATTACCCAGGAACAGGACGTTCCCAATTAGAGGCTTTCAGATTTATGATGGGCCCATTCATCTCACAAGGAGCACTTTCAAAAAATATGTGCCAACTCCAGATAGGTACAGCAGTGCAATTGGCTTCCTCATGAAGAATTCCTGGCAGATAACCCCCAGGAATAATATCTCCCTCGTGAAGTTTGGTCCACATGTCTCTCTGAATGTCTTTTTTGGAAAGCCTGGTCCCTGGTTTGAAGATTGTGAGATGGATGGTGATAAGAACTCCATATTCCATGACATTGATGGCTCTGTGACAGGATACAAGGATGCTTATGTGGGAAGAATGGACAACTACCTGATCCGCCATCCAAGCTGTGTAAATGTGTCTAAGTGGAATGCAGTGATCTGCAGTGGGACCTATGCACAGGTCTATGTACAGACATGGAGCACTCAGAATCTTTCTATGACCATTACACGAGATGAGTATCCGTCCAACCCTATGGTGCTCCGAGGTATTAATCAGAAGGCTGCCTTTCCACAGTACCAGCCTGTCGTCATGCTGGAGAAGGGTTATACCATCCACTGGAATGGGCCGGCACCACGGACTACATTTCTATACCTCGTCAACTTCAACAAGAATGACTGGATTCGAGTTGGCCTTTGCTATCCATCAAACACAAGTTTTCAAGTTACCTTTGGCTATTTGCAGCGGCAGAATGGCTCATTATCCAAAATCGAAGAATATGAGCCTGTGCATTCACTGGAAGAACTGCAAAGAAAGCAATCCGAGAGGAAATTCTATTTTGACTCCAGCACGGGGTTACTGTTTTTGTATCTCAAAGCCAAAAGCCACAGGCATGGCCACAGTTACTGTTCATCTCAGGGATGTGAAAGAGTCAAGATCCAAGCAGCCACAGACTCAAAGGACATCAGTAACTGCATGGCCAAAGCATACCCACAGTACTACAGAAAGCCGTCAGTGGTCAAGCGGATGCCGGCCATGCTCACTGGACTCTGTCAAGGCTGTGGCACTCGGCAGGTGGTGTTTACTAGTGATCCTCATAAAAGTTACCTCCCTGTGCAATTCCAGTCACCTGATAAAGCAGAAACCCAGCGTGGAGACCCGTCTGTTATTTCTGTCAATGGCACTGACTTTACCTTCCGAAGTGCAGGCGTCCTCCTCCTTGTTGTGGATCCGTGCAGCGTTCCATTCCGCTTGACGGAAAAAACGGTTTTTCCTCTTGCTGATGTCAGTCGCATTGAAGAGTATTTAAAAACAGGCATCCCTCCAAGGTCCATTGTTCTGTTGAGCACAAGAGGAGAAATAAAGCAGTTAAACATTTCACACTTACTAGTACCTCTGGGATTAGCCAAACCAGCTCATCTTTATGACAAAGGGAGTACCATATTTTTGGGATTCAGTGGAAACTTTAAACCATCATGGACTAAGCTATTTACCAGTCCTGCTGGACAGGGCCTTGGGGTGCTTGAACAATTCATACCTTTGCAGCTGGACGAATATGGTTGTCCCAGAGCCACCACTGTCCGCAGAAGAGACCTGGAACTGCTAAAGCAAGCTTCAAAAGCACATTAG
ORF Protein Sequence MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQRESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGDMLRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEGVSLSGFRVEVVDGVKLNLLDDVSSWKPGDQIVVASTDYSMYQAEEFTLLPCSECSHFQVKVKETPQFLHMGEIIDGVDMRAEVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHLCGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGLLTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHKEPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDANPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVGESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLMKNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKGYTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRKQSERKFYFDSSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKRMPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPCSVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIFLGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQASKAH

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1830-Ab Anti-CEIP2/ CEMIP2/ TMEM2 monoclonal antibody
    Target Antigen GM-Tg-g-MP1830-Ag CEMIP2 VLP (virus-like particle)
    ORF Viral Vector pGMAD001035 Human CEMIP2 Adenovirus plasmid
    ORF Viral Vector vGMAD001035 Human CEMIP2 Adenovirus particle


    Target information

    Target ID GM-MP1830
    Target Name CEMIP2
    Gene ID 23670, 83921, 703378, 309400, 101088960, 484171, 515491, 100055623
    Gene Symbol and Synonyms BHLHB2,CEMIP2,TMEM2
    Uniprot Accession Q9UHN6
    Uniprot Entry Name CEIP2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000135048
    Target Classification Not Available

    This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.