Anti-SLUR2/ SLURP2/ SLURP-2 monoclonal antibody

Anti-SLUR2/ SLURP2/ SLURP-2 antibody for FACS & in-vivo assay

Target products collectionGo to SLURP2/SLURP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2571-Ab-1/ GM-Tg-hg-MP2571-Ab-2Anti-Human SLURP2 monoclonal antibodyHuman
GM-Tg-rg-MP2571-Ab-1/ GM-Tg-rg-MP2571-Ab-2Anti-Rat SLURP2 monoclonal antibodyRat
GM-Tg-mg-MP2571-Ab-1/ GM-Tg-mg-MP2571-Ab-2Anti-Mouse SLURP2 monoclonal antibodyMouse
GM-Tg-cynog-MP2571-Ab-1/ GM-Tg-cynog-MP2571-Ab-2Anti-Cynomolgus/ Rhesus macaque SLURP2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2571-Ab-1/ GM-Tg-felg-MP2571-Ab-2Anti-Feline SLURP2 monoclonal antibodyFeline
GM-Tg-cang-MP2571-Ab-1/ GM-Tg-cang-MP2571-Ab-2Anti-Canine SLURP2 monoclonal antibodyCanine
GM-Tg-bovg-MP2571-Ab-1/ GM-Tg-bovg-MP2571-Ab-2Anti-Bovine SLURP2 monoclonal antibodyBovine
GM-Tg-equg-MP2571-Ab-1/ GM-Tg-equg-MP2571-Ab-2Anti-Equine SLURP2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2571-Ab-1/ GM-Tg-hg-MP2571-Ab-2; GM-Tg-rg-MP2571-Ab-1/ GM-Tg-rg-MP2571-Ab-2;
GM-Tg-mg-MP2571-Ab-1/ GM-Tg-mg-MP2571-Ab-2; GM-Tg-cynog-MP2571-Ab-1/ GM-Tg-cynog-MP2571-Ab-2;
GM-Tg-felg-MP2571-Ab-1/ GM-Tg-felg-MP2571-Ab-2; GM-Tg-cang-MP2571-Ab-1/ GM-Tg-cang-MP2571-Ab-2;
GM-Tg-bovg-MP2571-Ab-1/ GM-Tg-bovg-MP2571-Ab-2; GM-Tg-equg-MP2571-Ab-1/ GM-Tg-equg-MP2571-Ab-2
Products NameAnti-SLURP2 monoclonal antibody
Formatmab
Target NameSLURP2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLURP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SLUR2/ SLURP2/ SLURP-2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP002890human SLURP2 Lentivirus particle
    ORF Viral VectorpGMLP002890human SLURP2 Lentivirus plasmid


    Target information

    Target IDGM-MP2571
    Target NameSLURP2
    Gene ID432355,69462,315074,100428508,100683842,109496272
    Gene Symbol and Synonyms2300005B03Rik,LYNX1,RGD1308195,SLURP-2,SLURP2
    Uniprot AccessionP0DP57
    Uniprot Entry NameSLUR2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000283992
    Target ClassificationN/A

    The target: SLURP2, gene name: SLURP2, also named as SLURP-2. This gene encodes a novel, secreted member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This gene is mainly expressed in epithelial cells, including skin and keratinocytes, and is up-regulated in psoriatic skin lesions, suggesting its involvement in the pathophysiology of psoriasis. Alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (LYNX1) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.