Picture loading failed.

Pepsinogen II(PGII) - The Pepsinogens are gastric acid protease zymogens. They are divided into two distinct immunochemical groups. Pepsinogen I and II. Pepsinogen II is one of 4 aspartic proteinases: PG I, PG II, Cathepsin E and D. Pepsinogen II is produced primarily in the Oxyntic gland mucosa of the stomach, the gastric antrum and the duodenum. It is secreted mainly into the gastric lumen and into circulation. Pepsinogen II has little or no biological activity but in acid is converted to the active enzyme Pepsin which exhibits proteolytic actions. Unlike Pepsinogen I, Pepsinogen II is not normally found in the urine. Patients with pernicious anemia have low to non-detectable levels of Pepsinogen I but normal levels of Pepsinogen II. Pepsinogen II levels are slightly elevated in gastric ulcer. Patients with Zollinger-Ellison's syndrome exhibit greatly elevated levels.

Genemedi produces core diagnostic ingredients for test of gastric disease and related syndrome. GeneMedi offers paired diagnostics grade Pepsinogen II (PG II) antibodies (monoclonal antibody, mab) and Pepsinogen II (PG II) antigens for gastric disease rapid test kit of Pepsinogen II (PG II) testing in positive control, ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

All the antibodies and antigens for gastric disease test are suitable for in functional ELISA, and other immunoassays in dignostics. The antibodies can act as a capture antibody and detection antibody. The antigens can be used for antibodies rapid test of gastric disease.

Order information


Delivery impact due to the Coronavirus Outbreak

With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.

Catalog No. Size Price(In USD) Qty (Quantity) Sum(In USD)
GMP-PG II-Ag Size:1mg 1176
GMP-PG II-Ag Size:10mg 18963
GMP-PG II-Ag Size:100mg 48860
GMP-PG II-Ag ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description


Cat No. GMP-PG II-Ag
Product Name Recombinant Pepsinogen II (PG II, His Tag)
Expression platform E.coli
IsotypesRecombinant Antigen
Bioactivity validationPepsinogen II (PG II) Antibody Binding, Immunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
TagHis
Products descriptionRecombinant Pepsinogen II (PG II, His Tag) is produced by E.coli expression system with a 6His tag.
SpecicsNA
PurityPurity: ≥95% (SDS-PAGE)
Application positive control,ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.