SPRY3: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of SPRY3. The page also collects GeneMedi's different modalities and formats products for SPRY3 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SPRY3 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

Involved in negative regulation of MAPK cascade. Predicted to be located in membrane. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

Target IDGM-IP1814
Target NameSPRY3
Gene ID10251,236576,498159,703923,492271,101094659,539402,100062480
Gene Symbol and SynonymsGm1409,Gm391,RGD1562172,sprouty3,spry-3,SPRY3
Uniprot AccessionO43610
Uniprot Entry NameSPY3_HUMAN
Protein Sub-locationIntrocelluar Protein
CategoryCytokine Target
DiseaseN/A
Gene EnsemblENSG00000168939
Target ClassificationN/A


Pre-made anti-SPRY3 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-SPRY3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SPRY3 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-SPRY3 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabCytokine antibodyDetail



Recombinant multi-species SPY3/ SPRY3/ spry-3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPRY3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
SPRY3 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Cytokine Products for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse sprouty homolog 3 (Drosophila) (SPRY3) His+Avi (Biotinylated) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Protein sprouty homolog 3 is a protein that in humans is encoded by the SPRY3 gene.? The SPRY3 gene is one of the genes found in the pseudoautosomal regions of the human sex chromosomes (i.e. those 19 genes that are found on both the X and Y chromosome). It is located in the PAR2 region.

TargetSpeciesAntigen Product NameBioactivity validation of AntigenAntibody Product NameBioactivity validation of AntibodiesDetail
SPRY3Human, Cynomolgus/Rhesus macaque, rat, mousesprouty homolog 3 (Drosophila) (SPRY3) proteinAffintiy&bioactivity validated by ELISA, cell culture validatedAnti-SPRY3 monoclonal antibodyBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).Detail

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