GSDMD: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of GSDMD. The page also collects GeneMedi's different modalities and formats products for GSDMD in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GSDMD target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Target IDGM-MP2580
Target NameGSDMD
Gene ID79792,69146,315084,697137,609395,101089493,513939,100063519
Gene Symbol and Synonyms1810036L03Rik,DF5L,DFNA5L,FKSG10,GSDMD,GsdmD-1,GSDMDC1,M2-4
Uniprot AccessionP57764
Uniprot Entry NameGSDMD_HUMAN
Protein Sub-locationTransmembrane Protein
Category
DiseaseN/A
Gene EnsemblENSG00000104518
Target ClassificationN/A


Pre-made anti-GSDMD inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-GSDMD benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GSDMD mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-GSDMD monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional AntibodyDetail



Multi-species GSDMD/ DF5L/ DFNA5L VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GSDMD VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
GSDMD VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made GSDMD viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP003197human GSDMD Lentivirus plasmidNM_024736HumanLentivirus plasmidDetail
vGMLP003197human GSDMD Lentivirus particleNM_024736HumanLentivirus particleDetail
pGMAD000332mouse Gsdmd Adenovirus plasmidNM_026960.4MouseAdenovirus plasmidDetail
pGMAD000488house mouse Gsdmd Adenovirus plasmidNM_026960.4House MouseAdenovirus plasmidDetail
vGMAD000332mouse Gsdmd Adenovirus particleNM_026960.4MouseAdenovirus particleDetail
vGMAD000488house mouse Gsdmd Adenovirus particleNM_026960.4House MouseAdenovirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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