GSDMD: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of GSDMD. The page also collects GeneMedi's different modalities and formats products for GSDMD in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GSDMD target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
|Gene Symbol and Synonyms||1810036L03Rik,DF5L,DFNA5L,FKSG10,GSDMD,GsdmD-1,GSDMDC1,M2-4|
|Uniprot Entry Name||GSDMD_HUMAN|
|Protein Sub-location||Transmembrane Protein|
Pre-made anti-GSDMD inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-GSDMD benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GSDMD mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
|Antibody Name||Species||Format||Classified by tag||Detail|
|Anti-GSDMD monoclonal antibody||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||mab||FACS/Biofunctional Antibody||Detail|
Multi-species GSDMD/ DF5L/ DFNA5L VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GSDMD VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
|Products Name||Species||Expression Platform||Detail|
|GSDMD VLP (virus-like particle)||Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine||Mammalian cell||Products Developing|
Pre-made GSDMD viral vector in GM Promise-ORFTM
|Cat No.||Products name||NM ID||Species||Type||Detail|
|pGMLP003197||human GSDMD Lentivirus plasmid||NM_024736||Human||Lentivirus plasmid||Detail|
|vGMLP003197||human GSDMD Lentivirus particle||NM_024736||Human||Lentivirus particle||Detail|
|pGMAD000332||mouse Gsdmd Adenovirus plasmid||NM_026960.4||Mouse||Adenovirus plasmid||Detail|
|pGMAD000488||house mouse Gsdmd Adenovirus plasmid||NM_026960.4||House Mouse||Adenovirus plasmid||Detail|
|vGMAD000332||mouse Gsdmd Adenovirus particle||NM_026960.4||Mouse||Adenovirus particle||Detail|
|vGMAD000488||house mouse Gsdmd Adenovirus particle||NM_026960.4||House Mouse||Adenovirus particle||Detail|
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.