FSTL1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of FSTL1. The page also collects GeneMedi's different modalities and formats products for FSTL1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the FSTL1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]

Target IDGM-SE0225
Target NameFSTL1
Gene ID11167,14314,79210,713367,608384,101082337,534482,100070833
Gene Symbol and SynonymsFRP,FSL1,Fstl,FSTL1,MIR198,OCC-1,OCC1,TSC-36,tsc36
Uniprot AccessionQ12841,Q62632,Q58D84
Uniprot Entry NameFSTL1_HUMAN,FSTL1_RAT,FSTL1_BOVIN
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryCytokine Target
DiseaseOvary Cancer
Gene EnsemblENSG00000163430
Target ClassificationN/A


Pre-made anti-FSTL1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-FSTL1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FSTL1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-FSTL1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Cytokine antibodyDetail



Recombinant multi-species FSTL1/ FRP/ FSL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FSTL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
FSTL1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Cytokine Products for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces human, Cynomolgus/ Rhesus macaque, rat, mouse follistatin-like 1 (FSTL1) His+Avi (Biotinylated) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Follistatin-related protein 1 is a protein that in humans is encoded by the FSTL1 gene. This gene encodes a protein with similarity to follistatin, an BMP-4-binding protein. It binds to BMP-4 and TGF-??1, but not Activin A. It contains an FS module (a follistatin-like sequence containing 10 conserved cysteine residues), a Kazal-type serine protease inhibitor domain, 2 EF hand domains, and a Von Willebrand factor type C domain.

TargetSpeciesAntigen Product NameBioactivity validation of AntigenAntibody Product NameBioactivity validation of AntibodiesDetail
FSTL1Human, Cynomolgus/Rhesus macaque, rat, mousefollistatin-like 1 (FSTL1) proteinAffintiy&bioactivity validated by ELISA, cell culture validatedAnti-FSTL1 monoclonal antibodyBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).Detail

Click to check more Cytokine Products



Pre-made FSTL1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP001890human FSTL1 Lentivirus particleNM_007085.4HumanLentivirus particleDetail
pGMLP001890human FSTL1 Lentivirus plasmidNM_007085.4HumanLentivirus plasmidDetail
pGMAAV000038mouse Fstl1 AAV plasmidNM_008047.5MouseAAV plasmidDetail
vGMAAV000038mouse Fstl1 AAV particleNM_008047.5MouseAAV particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






GENEMEDI
Email: [email protected]   [email protected]
Telephone: +86-21-50478399   Fax: 86-21-50478399
Privacy Policy
<