GFRAL: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of GFRAL. The page also collects GeneMedi's different modalities and formats products for GFRAL in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GFRAL target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Enables glial cell-derived neurotrophic factor receptor activity and receptor tyrosine kinase binding activity. Involved in glial cell-derived neurotrophic factor receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of protein kinase B signaling. Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Target ID | GM-T37012 |
Target Name | GFRAL |
Gene ID | 389400 |
Gene Official Name | GFRAL |
Gene Alias | C6orf144, GRAL, UNQ9356, bA360D14.1 |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Cytokine Target |
Pre-made anti-GFRAL inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-GFRAL benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GFRAL mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Cat No. | Antibody Name | Format | Classified by tag | Order |
GM-Tg-hg-T37012-Ab | Anti-GFRAL monoclonal antibody | mab | Biofunctional antibody, Therapeutics Target antibody, Cytokine antibody | ![]() |