CD33: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of CD33. The page also collects GeneMedi's different modalities and formats products for CD33 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CD33 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]
Target ID | GM-T38950 |
Target Name | CD33 |
Gene ID | 945 |
Gene Official Name | CD33 |
Gene Alias | SIGLEC-3, SIGLEC3, p67 |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, INN Index, Immuno-oncology Target |
Pre-made CD33-specific INN-index biosimilar (antibody&conjugates)-Vadastuximab, actinium (225Ac) lintuzumab satetraxetan, Lintuzumab, Emerfetamab, Vixtimotamab, vadastuximab talirine, Gemtuzumab, gemtuzumab ozogamicin, Eluvixtamab
Anti-CD33 therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Pre-made anti-CD33 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark reference antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-CD33 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CD33 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Cat No. | Antibody Name | Format | Classified by tag | Order |
GM-Tg-hg-T38950-Ab | Anti-CD33 monoclonal antibody | mab | Biofunctional antibody, Therapeutics Target antibody | ![]() |