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It's the GeneMedi's summary page for Target/Biomarker Introduction of CACNA2D1. The page also collects GeneMedi's different modalities and formats products for CACNA2D1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CACNA2D1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Secreted Protein/Potential Cytokines.

The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014]

Target IDGM-T84316
Target NameCACNA2D1
Gene ID781
Gene Official NameCACNA2D1
Gene AliasCACNA2, CACNL2A, CCHL2A, LINC01112, lncRNA-N3
Protein Sub-locationSecreted Protein/Potential Cytokines
CategoryTherapeutics Target


Pre-made anti-CACNA2D1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-CACNA2D1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CACNA2D1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Cat No.Antibody NameFormatClassified by tagOrder
GM-Tg-hg-T84316-AbAnti-CACNA2D1 monoclonal antibodymabBiofunctional antibody, Therapeutics Target antibodymonoclonal antibody.




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