S6K1/RPS6KB1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of S6K1/RPS6KB1. The page also collects GeneMedi's different modalities and formats products for S6K1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the S6K1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
Target ID | GM-T94479 |
Target Name | S6K1 |
Gene ID | 6198,72508,83840,711979,480580,101092561,404181,100057481 |
Gene Symbol and Synonyms | 2610318I15Rik,p70 S6K-alpha,p70 S6KA,p70(S6K)-alpha,p70-alpha,p70-S6K,p70-S6K 1,p70/85s6k,p70s6k,P70S6K1,PS6K,RPS6KB1,S6K,S6K-beta-1,S6K1,STK14A |
Uniprot Accession | P23443,P67999,Q6TJY3 |
Uniprot Entry Name | KS6B1_HUMAN,KS6B1_RAT,KS6B1_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000108443 |
Target Classification | Kinase, Tumor-associated antigen (TAA) |
Pre-made anti-S6K1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-S6K1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-S6K1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-S6K1/RPS6KB1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species KS6B1/ S6K1/ RPS6KB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine S6K1/RPS6KB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
S6K1/RPS6KB1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made RPS6KB1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP001423 | human RPS6KB1 Lentivirus plasmid | NM_003161 | Human | Lentivirus plasmid | Detail |
vGMLP001423 | human RPS6KB1 Lentivirus particle | NM_003161 | Human | Lentivirus particle | Detail |
pGMLPm002997 | mouse Rps6kb1 Lentivirus plasmid | NM_001114334 | Mouse | Lentivirus plasmid | Detail |
vGMLPm002997 | mouse Rps6kb1 Lentivirus particle | NM_001114334 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.