Diagnostic antibodies and antigens for Tumor and Cancer testing: Thyroglobulin (TG), CA-125, SCC Ag, PIVKA-Ⅱ, ProGRP, Calcitonin, NSE, CA-724, HE4, CA15-3, CYFRA21-1, HER2, FER, HSP90α, S100B


Regardless of the advances in the cancer therapy, delayed symptoms and lack of successful diagnosis of cancer at early stage increased the death rate. Tumor-associated antigens (TAAs) and their antibodies have been identified as potential markers in cancer diagnosis and determination. TAAs and their antibodies-based detection of cancer have the advantages such as low-cost, and simple access, which attracted much attention for early cancer detection. For several reasons, tumor marker itself is typically insufficient to analyze disease conditions. Because, maximum number of markers have been produced by both normal and cancer cells. Several markers such as hyroglobulin (TG), cancer antigen 125 (CA-125), squamous cell carcinoma antigen (SCC Ag), Protein induced by vitamin K absence-II (PIVKA-II), Gastrin-releasing peptide (Pro-GRP), Calcitonin, Neuron specific enolase (NSE), Cancer Antigen 72-4 (CA-724), Human epididymis protein 4 (HE4), Cancer antigen 15-3 (CA15-3), cytokeratin-19 (CYFRA21-1), human epidermal growth factor receptor 2 (HER2), Ferritin (FER), Heat shock proteins 90-alpha (HSP90α), S100 proteins (S100B) and so on have been identified to be associated with the specific cancer. Detecting the quantity of these marker proteins from different samples may benefit from ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Genemedi supplies antibodies and antigens for Tumor and Cancer testing for a wide selection of choices (please see below).

TG CA-125 SCC Ag PIVKA-Ⅱ ProGRP Calcitonin NSE CA-724 HE4 CA15-3 CYFRA21-1 HER2 FER HSP90α S100B







Thyroglobulin (TG)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-TG-AbAnti-Thyroglobulin (TG) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Thyroglobulin (TG) protein binding, ELISA validated as capture antibody and detection antibody. Pair in TGlevel test and Tumor/Cancer evaluation.Picture loading failed.


cancer antigen 125 (CA-125)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-CA-125-AbAnti- cancer antigen 125 (CA-125) mouse monoclonal antibody(mAb) CHOMouse IgGHuman cancer antigen 125 (CA-125) protein binding, ELISA validated as capture antibody and detection antibody. Pair in CA-125level test and Tumor/Cancer evaluation.Picture loading failed.


squamous cell carcinoma antigen (SCC Ag)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-SCC Ag-AbAnti-squamous cell carcinoma antigen (SCC Ag) mouse monoclonal antibody(mAb) CHOMouse IgGHuman squamous cell carcinoma antigen (SCC Ag) protein binding, ELISA validated as capture antibody and detection antibody. Pair in SCC Aglevel test and Tumor/Cancer evaluation.Picture loading failed.


Protein induced by vitamin K absence-II (PIVKA-Ⅱ)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-PIVKA-Ⅱ-AbAnti-Protein induced by vitamin K absence-II (PIVKA-Ⅱ) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Protein induced by vitamin K absence-II (PIVKA-Ⅱ) protein binding, ELISA validated as capture antibody and detection antibody. Pair in PIVKA-Ⅱlevel test and Tumor/Cancer evaluation.Picture loading failed.


Gastrin-releasing peptide (ProGRP)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-ProGRP-AbAnti-Gastrin-releasing peptide (ProGRP) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Gastrin-releasing peptide (ProGRP) protein binding, ELISA validated as capture antibody and detection antibody. Pair in ProGRPlevel test and Tumor/Cancer evaluation.Picture loading failed.


Calcitonin (Calcitonin)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-Calcitonin-AbAnti-Calcitonin (Calcitonin) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Calcitonin (Calcitonin) protein binding, ELISA validated as capture antibody and detection antibody. Pair in Calcitoninlevel test and Tumor/Cancer evaluation.Picture loading failed.


Neuron specific enolase (NSE)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-NSE-AbAnti-Neuron specific enolase (NSE) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Neuron specific enolase (NSE) protein binding, ELISA validated as capture antibody and detection antibody. Pair in NSElevel test and Tumor/Cancer evaluation.Picture loading failed.


Cancer Antigen 72-4 (CA-724)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-CA-724-AbAnti-Cancer Antigen 72-4 (CA-724) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Cancer Antigen 72-4 (CA-724) protein binding, ELISA validated as capture antibody and detection antibody. Pair in CA-724level test and Tumor/Cancer evaluation.Picture loading failed.


Human epididymis protein 4 (HE4)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-HE4-AbAnti-Human epididymis protein 4 (HE4) mouse monoclonal antibody(mAb) CHOMouse IgGhuman epididymis protein 4 (HE4) protein binding, ELISA validated as capture antibody and detection antibody. Pair in HE4level test and Tumor/Cancer evaluation.Picture loading failed.


Cancer antigen 15-3 (CA15-3)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-CA15-3-AbAnti-Cancer antigen 15-3 (CA15-3) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Cancer antigen 15-3 (CA15-3) protein binding, ELISA validated as capture antibody and detection antibody. Pair in CA15-3level test and Tumor/Cancer evaluation.Picture loading failed.


soluble fragment of cytokeratin-19 (CYFRA21-1)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-CYFRA21-1-AbAnti-soluble fragment of cytokeratin-19 (CYFRA21-1) mouse monoclonal antibody(mAb) CHOMouse IgGHuman soluble fragment of cytokeratin-19 (CYFRA21-1) protein binding, ELISA validated as capture antibody and detection antibody. Pair in CYFRA21-1level test and Tumor/Cancer evaluation.Picture loading failed.


human epidermal growth factor receptor 2 (HER2)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-HER2-Ag;
GMP-HER2-Ab
Antigen: Recombinant human epidermal growth factor receptor 2 (HER2, His Tag);
Antibody: Anti-human epidermal growth factor receptor 2 (HER2) mouse monoclonal antibody(mAb)
Antigen: E.coli;
Antibody: CHO
Antigen: Recombinant Antigen;
Antibody: Mouse IgG
Antigen: human epidermal growth factor receptor 2 (HER2) Antibody Binding;
Antibody: human epidermal growth factor receptor 2 (HER2) protein binding, ELISA validated as capture antibody and detection antibody. Pair in HER2 test and Tumor/Cancer evaluation.
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Ferritin (FER)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-FER-Ag;
GMP-FER-Ab
Antigen: Recombinant Ferritin (FER, His Tag)
Antibody: Anti-Ferritin (FER) mouse monoclonal antibody(mAb)
Antigen: E.coli;
Antibody: CHO
Antigen: Recombinant Antigen;
Antibody: Mouse IgG
Antigen: Ferritin (FER) Antibody Binding;
Antibody: Human Ferritin (FER) protein binding, ELISA validated as capture antibody and detection antibody. Pair in FER level test and Tumor/Cancer evaluation.
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Heat shock proteins 90-alpha (HSP90α)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-HSP90α-AbAnti-Heat shock proteins 90-alpha (HSP90α) mouse monoclonal antibody(mAb) CHOMouse IgGHuman Heat shock proteins 90-alpha (HSP90α) protein binding, ELISA validated as capture antibody and detection antibody. Pair in HSP90αlevel test and Tumor/Cancer evaluation.Picture loading failed.


S100 proteins (S100B)

Cat No. Antibody/Antigen Name Expression platform Isotypes Bioactivity validation Order
GMP-S100B-AgRecombinant S100 proteins (S100B, His Tag)E.coliRecombinant AntigenS100 proteins (S100B) Antibody Binding, Immunogen in Sandwich ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCTPicture loading failed.



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