Diagnostic Heat shock proteins 90-alpha (HSP90α) antibodies (anti-Heat shock proteins 90-alpha, anti-HSP90α) for Tumor/Cancer HSP90α detection in ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.

Catalog Number: GMP-HSP90α-Ab

The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

Genemedi produces core diagnostic ingredients for test of Tumor/Cancer and related syndrome. GeneMedi offers paired diagnostics grade Heat shock proteins 90-alpha (HSP90α) ) antibodies (monoclonal antibody, mab) and Heat shock proteins 90-alpha (HSP90α) ) antigens for Tumor/Cancer rapid test kit of Heat shock proteins 90-alpha (HSP90α) ) testing in ELISA test,Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. All the antibodies and antigens for Tumor/Cancer test are suitable for in functional ELISA, and other immunoassays in dignostics.The antibodies can act as a capture antibody and detection antibody.The antigens can be used for antibodies rapid test of Tumor/Cancer.

Order information

Catalog No. Size Price(In USD) Qty (Quantity) Sum(In USD)
GMP-HSP90α-Ab-1 Size:1mg 1953
GMP-HSP90α-Ab-1 Size:10mg 13671
GMP-HSP90α-Ab-1 Size:100mg 95697
GMP-HSP90α-Ab-2 Size:1mg 1953
GMP-HSP90α-Ab-2 Size:10mg 13671
GMP-HSP90α-Ab-2 Size:100mg 95697
GMP-HSP90α-Ab ≥100mg Inquiry
Shipping Cost: 760.00
Total:

For more than 100mg, click here for inquiry. >>


Description


Cat No. GMP-HSP90α-Ab-1; GMP-HSP90α-Ab-2
Product Name Anti-Heat shock proteins 90-alpha (HSP90α) mouse monoclonal antibody(mAb)
Expression platform CHO
IsotypesMouse IgG
Bioactivity validationHuman Heat shock proteins 90-alpha (HSP90α) protein binding, ELISA validated as capture antibody and detection antibody. Pair in HSP90αlevel test and Tumor/Cancer evaluation.
TagmFc
Products descriptionAnti-Heat shock proteins 90-alpha (HSP90α) mouse monoclonal antibody(mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody pair.
Specicsmouse
PurityPurity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.