Human DUSP13/BEDP/DUSP13A ORF/cDNA clone-Adeno-associate virus(AAV) plasmid (NM_016364.3)

Cat. No.: pGMAAV001531
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human DUSP13/BEDP/DUSP13A Adeno-associated virus expression plasmid (ITR-vector) for DUSP13 AAV packaging, DUSP13 AAV production.The purified Human DUSP13/BEDP/DUSP13A AAV particle serves as an invaluable asset for in-depth in vivo DUSP13 studies, mechanism of action (MOA) research, and the evolution of DUSP13-associated gene therapy strategies.

Our GM-AAV ITR vector is optimized with the G-NEXT™ multi-serotypes AAV vector system. Explore the G-NEXT™ system in detail.

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Product Description

Catalog ID pGMAAV001531
Gene Name DUSP13
Accession Number NM_016364.3
Gene ID 51207
Species Human
Product Type Adeno-associate virus(AAV) plasmid (overexpression)
Insert Length 597 bp
Gene Alias BEDP,DUSP13A,DUSP13B,MDSP,SKRP4,TMDP
Fluorescent Reporter EGFP
Mammalian Cell Selection Null
Fusion Tag Null
Promoter CTNT
Resistance Amplicin
ORF Nucleotide Sequence ATGGACTCACTGCAGAAGCAGGACCTCCGGAGGCCCAAGATCCATGGGGCAGTCCAGGCATCTCCCTACCAGCCGCCCACATTGGCTTCGCTGCAGCGCTTGCTGTGGGTCCGTCAGGCTGCCACACTGAACCATATCGATGAGGTCTGGCCCAGCCTCTTCCTGGGAGATGCGTACGCAGCCCGGGACAAGAGCAAGCTGATCCAGCTGGGAATCACCCACGTTGTGAATGCCGCTGCAGGCAAGTTCCAGGTGGACACAGGTGCCAAATTCTACCGTGGAATGTCCCTGGAGTACTATGGCATCGAGGCGGACGACAACCCCTTCTTCGACCTCAGTGTCTACTTTCTGCCTGTTGCTCGATACATCCGAGCTGCCCTCAGTGTTCCCCAAGGCCGCGTGCTGGTACACTGTGCCATGGGGGTAAGCCGCTCTGCCACACTTGTCCTGGCCTTCCTCATGATCTGTGAGAACATGACGCTGGTAGAGGCCATCCAGACGGTGCAGGCCCACCGCAATATCTGCCCTAACTCAGGCTTCCTCCGGCAGCTCCAGGTTCTGGACAACCGACTGGGGCGGGAGACGGGGCGGTTCTGA
ORF Protein Sequence MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0731-Ab Anti-DUSP13 monoclonal antibody
    Target Antigen GM-Tg-g-IP0731-Ag DUSP13 protein
    ORF Viral Vector pGMLP004817 Human DUSP13 Lentivirus plasmid
    ORF Viral Vector pGMAAV001531 Human DUSP13 Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLP004817 Human DUSP13 Lentivirus particle
    ORF Viral Vector vGMAAV001531 Human DUSP13 Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-IP0731
    Target Name DUSP13
    Gene ID 51207, 27389, 704480, 361002, 101091309, 489054, 616048, 100072931
    Gene Symbol and Synonyms DUSP13,DUSP13A,DUSP13B,Gm1203,LMW-DSP6,MDSP,SKRP4,TMDP,TS-DSP6
    Uniprot Accession Q6B8I1, Q9UII6
    Uniprot Entry Name DS13A_HUMAN,DS13B_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000079393
    Target Classification Not Available

    Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and  differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.