Anti-DUSP13 monoclonal antibody
Pre-made anti-DUSP13 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-IP0731-Ab-1/ GM-Tg-hg-IP0731-Ab-2 | Anti-Human DUSP13 monoclonal antibody | Human |
GM-Tg-rg-IP0731-Ab-1/ GM-Tg-rg-IP0731-Ab-2 | Anti-Rat DUSP13 monoclonal antibody | Rat |
GM-Tg-mg-IP0731-Ab-1/ GM-Tg-mg-IP0731-Ab-2 | Anti-Mouse DUSP13 monoclonal antibody | Mouse |
GM-Tg-cynog-IP0731-Ab-1/ GM-Tg-cynog-IP0731-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DUSP13 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-IP0731-Ab-1/ GM-Tg-felg-IP0731-Ab-2 | Anti-Feline DUSP13 monoclonal antibody | Feline |
GM-Tg-cang-IP0731-Ab-1/ GM-Tg-cang-IP0731-Ab-2 | Anti-Canine DUSP13 monoclonal antibody | Canine |
GM-Tg-bovg-IP0731-Ab-1/ GM-Tg-bovg-IP0731-Ab-2 | Anti-Bovine DUSP13 monoclonal antibody | Bovine |
GM-Tg-equg-IP0731-Ab-1/ GM-Tg-equg-IP0731-Ab-2 | Anti-Equine DUSP13 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-IP0731-Ab-1/ GM-Tg-hg-IP0731-Ab-2; GM-Tg-rg-IP0731-Ab-1/ GM-Tg-rg-IP0731-Ab-2; GM-Tg-mg-IP0731-Ab-1/ GM-Tg-mg-IP0731-Ab-2; GM-Tg-cynog-IP0731-Ab-1/ GM-Tg-cynog-IP0731-Ab-2; GM-Tg-felg-IP0731-Ab-1/ GM-Tg-felg-IP0731-Ab-2; GM-Tg-cang-IP0731-Ab-1/ GM-Tg-cang-IP0731-Ab-2; GM-Tg-bovg-IP0731-Ab-1/ GM-Tg-bovg-IP0731-Ab-2; GM-Tg-equg-IP0731-Ab-1/ GM-Tg-equg-IP0731-Ab-2 |
Products Name | Anti-DUSP13 monoclonal antibody |
Format | mab |
Target Name | DUSP13 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-DUSP13 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-IP0731-Ag-1 | Recombinant multi-species DS13A/ DS13B/ DUSP13 protein |
ORF Viral Vector | pGMLP004817 | human DUSP13 Lentivirus plasmid |
ORF Viral Vector | vGMLP004817 | human DUSP13 Lentivirus particle |
ORF Viral Vector | pGMLPm004633 | mouse Dusp13 Lentivirus plasmid |
ORF Viral Vector | vGMLPm004633 | mouse Dusp13 Lentivirus particle |
Target information
Target ID | GM-IP0731 |
Target Name | DUSP13 |
Gene ID | 51207,27389,361002,704480,489054,101091309,616048,100072931 |
Gene Symbol and Synonyms | DUSP13,DUSP13A,DUSP13B,Gm1203,LMW-DSP6,MDSP,SKRP4,™DP,TS-DSP6 |
Uniprot Accession | Q6B8I1, Q9UII6 |
Uniprot Entry Name | DS13B_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000079393 |
Target Classification | N/A |
The target: DUSP13, gene name: DUSP13, also named as BEDPA, DUSP13B, MDSP, SKRP4, ™DP, DUSP13. Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.