Anti-DUSP13 monoclonal antibody

Pre-made anti-DUSP13 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to DUSP13/DUSP13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP0731-Ab-1/ GM-Tg-hg-IP0731-Ab-2Anti-Human DUSP13 monoclonal antibodyHuman
GM-Tg-rg-IP0731-Ab-1/ GM-Tg-rg-IP0731-Ab-2Anti-Rat DUSP13 monoclonal antibodyRat
GM-Tg-mg-IP0731-Ab-1/ GM-Tg-mg-IP0731-Ab-2Anti-Mouse DUSP13 monoclonal antibodyMouse
GM-Tg-cynog-IP0731-Ab-1/ GM-Tg-cynog-IP0731-Ab-2Anti-Cynomolgus/ Rhesus macaque DUSP13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP0731-Ab-1/ GM-Tg-felg-IP0731-Ab-2Anti-Feline DUSP13 monoclonal antibodyFeline
GM-Tg-cang-IP0731-Ab-1/ GM-Tg-cang-IP0731-Ab-2Anti-Canine DUSP13 monoclonal antibodyCanine
GM-Tg-bovg-IP0731-Ab-1/ GM-Tg-bovg-IP0731-Ab-2Anti-Bovine DUSP13 monoclonal antibodyBovine
GM-Tg-equg-IP0731-Ab-1/ GM-Tg-equg-IP0731-Ab-2Anti-Equine DUSP13 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP0731-Ab-1/ GM-Tg-hg-IP0731-Ab-2; GM-Tg-rg-IP0731-Ab-1/ GM-Tg-rg-IP0731-Ab-2;
GM-Tg-mg-IP0731-Ab-1/ GM-Tg-mg-IP0731-Ab-2; GM-Tg-cynog-IP0731-Ab-1/ GM-Tg-cynog-IP0731-Ab-2;
GM-Tg-felg-IP0731-Ab-1/ GM-Tg-felg-IP0731-Ab-2; GM-Tg-cang-IP0731-Ab-1/ GM-Tg-cang-IP0731-Ab-2;
GM-Tg-bovg-IP0731-Ab-1/ GM-Tg-bovg-IP0731-Ab-2; GM-Tg-equg-IP0731-Ab-1/ GM-Tg-equg-IP0731-Ab-2
Products NameAnti-DUSP13 monoclonal antibody
Formatmab
Target NameDUSP13
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-DUSP13 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP0731-Ag-1Recombinant multi-species DS13A/ DS13B/ DUSP13 protein
    ORF Viral VectorpGMLP004817human DUSP13 Lentivirus plasmid
    ORF Viral VectorvGMLP004817human DUSP13 Lentivirus particle
    ORF Viral VectorpGMLPm004633mouse Dusp13 Lentivirus plasmid
    ORF Viral VectorvGMLPm004633mouse Dusp13 Lentivirus particle


    Target information

    Target IDGM-IP0731
    Target NameDUSP13
    Gene ID51207,27389,361002,704480,489054,101091309,616048,100072931
    Gene Symbol and SynonymsDUSP13,DUSP13A,DUSP13B,Gm1203,LMW-DSP6,MDSP,SKRP4,™DP,TS-DSP6
    Uniprot AccessionQ6B8I1, Q9UII6
    Uniprot Entry NameDS13B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000079393
    Target ClassificationN/A

    The target: DUSP13, gene name: DUSP13, also named as BEDPA, DUSP13B, MDSP, SKRP4, ™DP, DUSP13. Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and  differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.