Human DAB2/DOC-2/ DOC2 ORF/cDNA clone-Adenovirus plasmid (NM_001343)

Pre-made Human DAB2/DOC-2/ DOC2 adenoviral expression plasmid for DAB2 adenovirus packaging, DAB2 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

Target products collectionGo to DAB2/DOC-2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAD000123 Human DAB2 Adenovirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAD000123
Gene Name DAB2
Accession Number NM_001343
Gene ID 1601
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 2313 bp
Gene Alias DOC-2, DOC2
Fluorescent Reporter EGFP
Mammalian Cell Selection
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2075-Ab Anti-DAB2/ DOC-2/ DOC2 monoclonal antibody
    Target Antigen GM-Tg-g-MP2075-Ag DAB2 VLP (virus-like particle)
    ORF Viral Vector pGMAD000123 Human DAB2 Adenovirus plasmid
    ORF Viral Vector vGMAD000123 Human DAB2 Adenovirus particle


    Target information

    Target ID GM-MP2075
    Target Name DAB2
    Gene ID 1601, 13132, 694349, 79128, 101096539, 479353, 509221, 100066655
    Gene Symbol and Synonyms 5730435J12Rik,D15Wsu122e,D630005B22Rik,DAB2,DOC-2,DOC2,p96
    Uniprot Accession P98082
    Uniprot Entry Name DAB2_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000153071
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.