Human DAB2/DOC-2/ DOC2 ORF/cDNA clone-Adenovirus plasmid (NM_001343)
Pre-made Human DAB2/DOC-2/ DOC2 adenoviral expression plasmid for DAB2 adenovirus packaging, DAB2 adenovirus.
Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMAD000123 | Human DAB2 Adenovirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMAD000123 |
Gene Name | DAB2 |
Accession Number | NM_001343 |
Gene ID | 1601 |
Species | Human |
Product Type | Adenovirus plasmid (overexpression) |
Insert Length | 2313 bp |
Gene Alias | DOC-2, DOC2 |
Fluorescent Reporter | EGFP |
Mammalian Cell Selection | |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-MP2075-Ab | Anti-DAB2/ DOC-2/ DOC2 monoclonal antibody |
Target Antigen | GM-Tg-g-MP2075-Ag | DAB2 VLP (virus-like particle) |
ORF Viral Vector | pGMAD000123 | Human DAB2 Adenovirus plasmid |
ORF Viral Vector | vGMAD000123 | Human DAB2 Adenovirus particle |
Target information
Target ID | GM-MP2075 |
Target Name | DAB2 |
Gene ID | 1601, 13132, 694349, 79128, 101096539, 479353, 509221, 100066655 |
Gene Symbol and Synonyms | 5730435J12Rik,D15Wsu122e,D630005B22Rik,DAB2,DOC-2,DOC2,p96 |
Uniprot Accession | P98082 |
Uniprot Entry Name | DAB2_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Not Available |
Disease | Cancer |
Gene Ensembl | ENSG00000153071 |
Target Classification | Tumor-associated antigen (TAA) |
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.