Human IL9/HP40/IL-9 ORF/cDNA clone-Lentivirus plasmid (NM_000590)

Cat. No.: pGMLP-IL-012
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human IL9/HP40/IL-9 Lentiviral expression plasmid for IL9 lentivirus packaging, IL9 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP-IL-012
Gene Name IL9
Accession Number NM_000590
Gene ID 3578
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 435 bp
Gene Alias HP40,IL-9,P40
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCTTCTGGCCATGGTCCTTACCTCTGCCCTGCTCCTGTGCTCCGTGGCAGGCCAGGGGTGTCCAACCTTGGCGGGGATCCTGGACATCAACTTCCTCATCAACAAGATGCAGGAAGATCCAGCTTCCAAGTGCCACTGCAGTGCTAATGTGACCAGTTGTCTCTGTTTGGGCATTCCCTCTGACAACTGCACCAGACCATGCTTCAGTGAGAGACTGTCTCAGATGACCAATACCACCATGCAAACAAGATACCCACTGATTTTCAGTCGGGTGAAAAAATCAGTTGAAGTACTAAAGAACAACAAGTGTCCATATTTTTCCTGTGAACAGCCATGCAACCAAACCACGGCAGGCAACGCGCTGACATTTCTGAAGAGTCTTCTGGAAATTTTCCAGAAAGAAAAGATGAGAGGGATGAGAGGCAAGATATGA
ORF Protein Sequence MLLAMVLTSALLLCSVAGQGCPTLAGILDINFLINKMQEDPASKCHCSANVTSCLCLGIPSDNCTRPCFSERLSQMTNTTMQTRYPLIFSRVKKSVEVLKNNKCPYFSCEQPCNQTTAGNALTFLKSLLEIFQKEKMRGMRGKI

Reference




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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-185 Pre-Made Enokizumab biosimilar, Whole mAb, Anti-IL9 Antibody: Anti-HP40/IL-9/P40 therapeutic antibody
    Target Antibody GM-Tg-g-T67079-Ab Anti-IL9/ HP40/ IL-9 functional antibody
    Target Antigen GM-Tg-g-T67079-Ag IL9 protein
    ORF Viral Vector pGMLP001893 Human IL9 Lentivirus plasmid
    ORF Viral Vector pGMAP000407 Human IL9 Adenovirus plasmid
    ORF Viral Vector pGMLP-IL-012 Human IL9 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-095 Human IL9 Adenovirus plasmid
    ORF Viral Vector vGMLP001893 Human IL9 Lentivirus particle
    ORF Viral Vector vGMAP000407 Human IL9 Adenovirus particle
    ORF Viral Vector vGMLP-IL-012 Human IL9 Lentivirus particle
    ORF Viral Vector vGMAP-IL-095 Human IL9 Adenovirus particle


    Target information

    Target ID GM-T67079
    Target Name IL9
    Gene ID 3578, 16198, 712292, 116558, 101088458, 100682918, 613392, 100062710
    Gene Symbol and Synonyms HP40,IL-9,IL9,P40
    Uniprot Accession P15248
    Uniprot Entry Name IL9_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, INN Index
    Disease Hodgkin's lymphoma
    Gene Ensembl ENSG00000145839
    Target Classification Not Available

    The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]



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