Human GHRH/GHRF/GRF ORF/cDNA clone-Lentivirus plasmid (NM_001184731)

Cat. No.: pGMLP000190
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human GHRH/GHRF/GRF Lentiviral expression plasmid for GHRH lentivirus packaging, GHRH lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000190
Gene Name GHRH
Accession Number NM_001184731
Gene ID 2691
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 324 bp
Gene Alias GHRF,GRF,INN
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCACTCTGGGTGTTCTTCTTTGTGATCCTCACCCTCAGCAACAGCTCCCACTGCTCCCCACCTCCCCCTTTGACCCTCAGGATGCGGCGGTATGCAGATGCCATCTTCACCAACAGCTACCGGAAGGTGCTGGGCCAGCTGTCCGCCCGCAAGCTGCTCCAGGACATCATGAGCAGGCAGCAGGGAGAGAGCAACCAAGAGCGAGGAGCAAGGGCACGGCTTGGTCGTCAGGTAGACAGCATGTGGGCAGAACAAAAGCAAATGGAATTGGAGAGCATCCTGGTGGCCCTGCTGCAGAAGCACAGGAACTCCCAGGGATGA
ORF Protein Sequence MPLWVFFFVILTLSNSSHCSPPPPLTLRMRRYADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARLGRQVDSMWAEQKQMELESILVALLQKHRNSQG

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0946-Ab Anti-SLIB/ GHRH/ GHRF functional antibody
    Target Antigen GM-Tg-g-SE0946-Ag GHRH protein
    ORF Viral Vector pGMLP000190 Human GHRH Lentivirus plasmid
    ORF Viral Vector vGMLP000190 Human GHRH Lentivirus particle


    Target information

    Target ID GM-SE0946
    Target Name GHRH
    Gene ID 2691, 14601, 701284, 29446, 101101046, 485863, 281191, 111769907
    Gene Symbol and Synonyms GHRF,GHRH,GRF,INN
    Uniprot Accession P01286
    Uniprot Entry Name SLIB_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000118702
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]



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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.