Human PTGES/MGST-IV/MGST1-L1 ORF/cDNA clone-Lentivirus plasmid (NM_004878)

Cat. No.: pGMLP000341
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human PTGES/MGST-IV/MGST1-L1 Lentiviral expression plasmid for PTGES lentivirus packaging, PTGES lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000341
Gene Name PTGES
Accession Number NM_004878
Gene ID 9536
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 459 bp
Gene Alias MGST-IV,MGST1-L1,MGST1L1,MPGES,mPGES-1,PGES,PIG12,PP102,PP1294,TP53I12
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCCTGCCCACAGCCTGGTGATGAGCAGCCCGGCCCTCCCGGCCTTCCTGCTCTGCAGCACGCTGCTGGTCATCAAGATGTACGTGGTGGCCATCATCACGGGCCAAGTGAGGCTGCGGAAGAAGGCCTTTGCCAACCCCGAGGATGCCCTGAGACACGGAGGCCCCCAGTATTGCAGGAGCGACCCCGACGTGGAACGCTGCCTCAGGGCCCACCGGAACGACATGGAGACCATCTACCCCTTCCTTTTCCTGGGCTTCGTCTACTCCTTTCTGGGTCCTAACCCTTTTGTCGCCTGGATGCACTTCCTGGTCTTCCTCGTGGGCCGTGTGGCACACACCGTGGCCTACCTGGGGAAGCTGCGGGCACCCATCCGCTCCGTGACCTACACCCTGGCCCAGCTCCCCTGCGCCTCCATGGCTCTGCAGATCCTCTGGGAAGCGGCCCGCCACCTGTGA
ORF Protein Sequence MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0039-Ab Anti-PTGES monoclonal antibody
    Target Antigen GM-Tg-g-IP0039-Ag PTGES protein
    ORF Viral Vector pGMLP000341 Human PTGES Lentivirus plasmid
    ORF Viral Vector pGMPC001111 Human PTGES Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000341 Human PTGES Lentivirus particle


    Target information

    Target ID GM-IP0039
    Target Name PTGES
    Gene ID 9536, 64292, 716657, 59103, 101086187, 480698, 282019, 100034143
    Gene Symbol and Synonyms 2410099E23Rik,D2Ertd369e,MGST-IV,MGST1-L1,MGST1L1,MPGES,mPGES-1,PGES,PIG12,PP102,PP1294,PTGES,TP53I12
    Uniprot Accession O14684
    Uniprot Entry Name PTGES_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Not Available
    Gene Ensembl ENSG00000148344
    Target Classification Not Available

    The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]



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