Human BNIP3L/BNIP3a/NIX ORF/cDNA clone-Lentivirus plasmid (NM_004331)

Cat. No.: pGMLP000351
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human BNIP3L/BNIP3a/NIX Lentiviral expression plasmid for BNIP3L lentivirus packaging, BNIP3L lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000351
Gene Name BNIP3L
Accession Number NM_004331
Gene ID 665
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 660 bp
Gene Alias BNIP3a,NIX
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTCGTCCCACCTAGTCGAGCCGCCGCCGCCCCTGCACAACAACAACAACAACTGCGAGGAAAATGAGCAGTCTCTGCCCCCGCCGGCCGGCCTCAACAGTTCCTGGGTGGAGCTACCCATGAACAGCAGCAATGGCAATGATAATGGCAATGGGAAAAATGGGGGGCTGGAACACGTACCATCCTCATCCTCCATCCACAATGGAGACATGGAGAAGATTCTTTTGGATGCACAACATGAATCAGGACAGAGTAGTTCCAGAGGCAGTTCTCACTGTGACAGCCCTTCGCCACAAGAAGATGGGCAGATCATGTTTGATGTGGAAATGCACACCAGCAGGGACCATAGCTCTCAGTCAGAAGAAGAAGTTGTAGAAGGAGAGAAGGAAGTCGAGGCTTTGAAGAAAAGTGCGGACTGGGTATCAGACTGGTCCAGTAGACCCGAAAACATTCCACCCAAGGAGTTCCACTTCAGACACCCTAAACGTTCTGTGTCTTTAAGCATGAGGAAAAGTGGAGCCATGAAGAAAGGGGGTATTTTCTCCGCAGAATTTCTGAAGGTGTTCATTCCATCTCTCTTCCTTTCTCATGTTTTGGCTTTGGGGCTAGGCATCTATATTGGAAAGCGACTGAGCACACCCTCTGCCAGCACCTACTGA
ORF Protein Sequence MSSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0427-Ab Anti-BNIP3L monoclonal antibody
    Target Antigen GM-Tg-g-IP0427-Ag BNIP3L protein
    ORF Viral Vector pGMLP000351 Human BNIP3L Lentivirus plasmid
    ORF Viral Vector pGMLP-SPh-117 Human BNIP3L Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-257 Human BNIP3L Adenovirus plasmid
    ORF Viral Vector pGMPC000336 Human BNIP3L Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000351 Human BNIP3L Lentivirus particle
    ORF Viral Vector vGMLP-SPh-117 Human BNIP3L Lentivirus particle
    ORF Viral Vector vGMAP-SPh-257 Human BNIP3L Adenovirus particle


    Target information

    Target ID GM-IP0427
    Target Name BNIP3L
    Gene ID 665, 12177, 641440, 140923, 101099293, 608552, 534615, 100054317
    Gene Symbol and Synonyms BNIP3a,BNIP3L,D14Ertd719e,Nip3L,NIX,UV93
    Uniprot Accession O60238
    Uniprot Entry Name BNI3L_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000104765
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c. [provided by RefSeq, Feb 2015]



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