Human LRAT/LCA14 ORF/cDNA clone-Lentivirus plasmid (NM_004744)

Cat. No.: pGMLP000561
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human LRAT/LCA14 Lentiviral expression plasmid for LRAT lentivirus packaging, LRAT lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000561
Gene Name LRAT
Accession Number NM_004744
Gene ID 9227
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 693 bp
Gene Alias LCA14
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAAGAACCCCATGCTGGAGGTGGTGTCTTTACTACTGGAGAAGCTGCTCCTCATCTCCAACTTCACGCTCTTTAGTTCGGGCGCCGCGGGCGAAGACAAAGGGAGGAACAGTTTTTATGAAACCAGCTCTTTCCACCGAGGCGACGTGCTGGAGGTGCCCCGGACCCACCTGACCCACTATGGCATCTACCTAGGAGACAACCGTGTTGCCCACATGATGCCCGACATCCTGTTGGCCCTGACAGACGACATGGGGCGCACGCAGAAGGTGGTCTCCAACAAGCGTCTCATCCTGGGCGTTATTGTCAAAGTGGCCAGCATCCGCGTGGACACAGTGGAGGACTTCGCCTACGGAGCTAACATCCTGGTCAATCACCTGGACGAGTCCCTCCAGAAAAAGGCACTGCTCAACGAGGAGGTGGCGCGGAGGGCTGAAAAGCTGCTGGGCTTTACCCCCTACAGCCTGCTGTGGAACAACTGCGAGCACTTCGTGACCTACTGCAGATATGGCACCCCGATCAGTCCCCAGTCCGACAAGTTTTGTGAGACTGTGAAGATAATTATTCGTGATCAGAGAAGTGTTCTTGCTTCAGCAGTCTTGGGATTGGCGTCTATAGTCTGTACGGGCTTGGTATCATACACTACCCTTCCTGCAATTTTTATTCCATTCTTCCTATGGATGGCTGGCTAA
ORF Protein Sequence MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG

Reference




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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP1105-Ab Anti-LRAT monoclonal antibody
    Target Antigen GM-Tg-g-IP1105-Ag LRAT protein
    ORF Viral Vector pGMLP000561 Human LRAT Lentivirus plasmid
    ORF Viral Vector pGMAAV001537 Human LRAT Adeno-associate virus(AAV) plasmid
    ORF Viral Vector pGMAAV001538 Human LRAT Adeno-associate virus(AAV) plasmid
    ORF Viral Vector vGMLP000561 Human LRAT Lentivirus particle
    ORF Viral Vector vGMAAV001537 Human LRAT Adeno-associate virus(AAV) particle
    ORF Viral Vector vGMAAV001538 Human LRAT Adeno-associate virus(AAV) particle


    Target information

    Target ID GM-IP1105
    Target Name LRAT
    Gene ID 9227, 79235, 698871, 64047, 101092432, 482660, 281285, 100069704
    Gene Symbol and Synonyms 1300010A18Rik,LCA14,LRAT
    Uniprot Accession O95237
    Uniprot Entry Name LRAT_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000121207
    Target Classification Not Available

    The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]



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