Human GLIPR1/CRISP7/GLIPR ORF/cDNA clone-Lentivirus plasmid (NM_006851)
Cat. No.: pGMLP000567
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human GLIPR1/CRISP7/GLIPR Lentiviral expression plasmid for GLIPR1 lentivirus packaging, GLIPR1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product Description
Catalog ID | pGMLP000567 |
Gene Name | GLIPR1 |
Accession Number | NM_006851 |
Gene ID | 11010 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 801 bp |
Gene Alias | CRISP7,GLIPR,RTVP1 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGCGTGTCACACTTGCTACAATAGCCTGGATGGTTTCTTTTGTCTCCAATTATTCACACACAGCAAATATTTTGCCAGATATCGAAAATGAAGATTTCATCAAAGACTGCGTTCGAATCCATAACAAGTTCCGATCAGAGGTGAAACCAACAGCCAGTGATATGCTATACATGACTTGGGACCCAGCACTAGCCCAAATTGCAAAAGCATGGGCCAGCAATTGCCAGTTTTCACATAATACACGGCTGAAGCCACCCCACAAGCTGCACCCAAACTTCACTTCACTGGGAGAGAACATCTGGACTGGGTCTGTGCCCATTTTTTCTGTGTCTTCCGCCATCACAAACTGGTATGACGAAATCCAGGACTATGACTTCAAGACTCGGATATGCAAAAAAGTCTGTGGCCACTACACTCAGGTTGTTTGGGCAGATAGTTACAAAGTTGGCTGCGCAGTTCAATTTTGCCCTAAAGTTTCTGGCTTTGACGCTCTTTCCAATGGAGCACATTTTATATGCAACTACGGACCAGGAGGGAATTACCCAACTTGGCCATATAAGAGAGGAGCCACCTGCAGTGCCTGCCCCAATAATGACAAGTGTTTGGACAATCTCTGTGTTAACCGACAGCGAGACCAAGTCAAACGTTACTACTCTGTTGTATATCCAGGCTGGCCCATATATCCACGTAACAGATACACTTCTCTCTTTCTCATTGTTAATTCAGTAATTCTAATACTGTCTGTTATAATTACCATTTTGGTACAGCACAAGTACCCTAATTTAGTTCTTTTGGACTAA |
ORF Protein Sequence | MRVTLATIAWMVSFVSNYSHTANILPDIENEDFIKDCVRIHNKFRSEVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSVSSAITNWYDEIQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAHFICNYGPGGNYPTWPYKRGATCSACPNNDKCLDNLCVNRQRDQVKRYYSVVYPGWPIYPRNRYTSLFLIVNSVILILSVIITILVQHKYPNLVLLD |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T70201-Ab | Anti-GLIP1/ GLIPR1/ CRISP7 monoclonal antibody |
Target Antigen | GM-Tg-g-T70201-Ag | GLIPR1 VLP (virus-like particle) |
ORF Viral Vector | pGMLP000567 | Human GLIPR1 Lentivirus plasmid |
ORF Viral Vector | vGMLP000567 | Human GLIPR1 Lentivirus particle |
Target information
Target ID | GM-T70201 |
Target Name | GLIPR1 |
Gene ID | 11010, 73690, 718956, 299783, 101087587, 474452, 767905, 100058283 |
Gene Symbol and Synonyms | 2410114O14Rik,CRISP7,GLIPR,GLIPR1,mRTVP-1,RTVP-1,RTVP1 |
Uniprot Accession | P48060 |
Uniprot Entry Name | GLIP1_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000139278 |
Target Classification | Not Available |
This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
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