Human HCST/DAP10/KAP10 ORF/cDNA clone-Lentivirus plasmid (NM_014266)

Cat. No.: pGMLP000743
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human HCST/DAP10/KAP10 Lentiviral expression plasmid for HCST lentivirus packaging, HCST lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000743
Gene Name HCST
Accession Number NM_014266
Gene ID 10870
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 282 bp
Gene Alias DAP10,KAP10,PIK3AP
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGATCCATCTGGGTCACATCCTCTTCCTGCTTTTGCTCCCAGTGGCTGCAGCTCAGACGACTCCAGGAGAGAGATCATCACTCCCTGCCTTTTACCCTGGCACTTCAGGCTCTTGTTCCGGATGTGGGTCCCTCTCTCTGCCGCTCCTGGCAGGCCTCGTGGCTGCTGATGCGGTGGCATCGCTGCTCATCGTGGGGGCGGTGTTCCTGTGCGCACGCCCACGCCGCAGCCCCGCCCAAGAAGATGGCAAAGTCTACATCAACATGCCAGGCAGGGGCTGA
ORF Protein Sequence MIHLGHILFLLLLPVAAAQTTPGERSSLPAFYPGTSGSCSGCGSLSLPLLAGLVAADAVASLLIVGAVFLCARPRRSPAQEDGKVYINMPGRG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0574-Ab Anti-HCST/ DAP10/ KAP10 monoclonal antibody
    Target Antigen GM-Tg-g-MP0574-Ag HCST VLP (virus-like particle)
    ORF Viral Vector pGMLP000743 Human HCST Lentivirus plasmid
    ORF Viral Vector vGMLP000743 Human HCST Lentivirus particle


    Target information

    Target ID GM-MP0574
    Target Name HCST
    Gene ID 10870, 23900, 574152, 474146, 101097286, 612627, 767892, 100060115
    Gene Symbol and Synonyms DAP10,HCST,KAP10,PIK3AP
    Uniprot Accession Q9UBK5
    Uniprot Entry Name HCST_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000126264
    Target Classification Not Available

    This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]



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