Human NPPA/ANF/ANP ORF/cDNA clone-Lentivirus plasmid (NM_006172.3)

Cat. No.: pGMLP000970
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human NPPA/ANF/ANP Lentiviral expression plasmid for NPPA lentivirus packaging, NPPA lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP000970
Gene Name NPPA
Accession Number NM_006172.3
Gene ID 4878
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 456 bp
Gene Alias ANF,ANP,ATFB6,ATRST2,CDD,CDD-ANF,CDP,PND
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGAGCTCCTTCTCCACCACCACCGTGAGCTTCCTCCTTTTACTGGCATTCCAGCTCCTAGGTCAGACCAGAGCTAATCCCATGTACAATGCCGTGTCCAACGCAGACCTGATGGATTTCAAGAATTTGCTGGACCATTTGGAAGAAAAGATGCCTTTAGAAGATGAGGTCGTGCCCCCACAAGTGCTCAGTGAGCCGAATGAAGAAGCGGGGGCTGCTCTCAGCCCCCTCCCTGAGGTGCCTCCCTGGACCGGGGAAGTCAGCCCAGCCCAGAGAGATGGAGGTGCCCTCGGGCGGGGCCCCTGGGACTCCTCTGATCGATCTGCCCTCCTAAAAAGCAAGCTGAGGGCGCTGCTCACTGCCCCTCGGAGCCTGCGGAGATCCAGCTGCTTCGGGGGCAGGATGGACAGGATTGGAGCCCAGAGCGGACTGGGCTGTAACAGCTTCCGGTACTGA
ORF Protein Sequence MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLTAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-SE0373-Ab Anti-ANF/ NPPA/ ANP functional antibody
    Target Antigen GM-Tg-g-SE0373-Ag NPPA protein
    ORF Viral Vector pGMLP000970 Human NPPA Lentivirus plasmid
    ORF Viral Vector pGMLV002264 Human NPPA Lentivirus plasmid
    ORF Viral Vector vGMLP000970 Human NPPA Lentivirus particle
    ORF Viral Vector vGMLV002264 Human NPPA Lentivirus particle


    Target information

    Target ID GM-SE0373
    Target Name NPPA
    Gene ID 4878, 230899, 714994, 24602, 101100575, 608289, 281355, 100034201
    Gene Symbol and Synonyms ANF,ANP,ATFB6,ATRST2,CDD,CDD-ANF,CDP,NPPA,PND,preproANF,preproANP,proANF,proANP,RATANF
    Uniprot Accession P01160
    Uniprot Entry Name ANF_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Diagnostics Biomarker
    Disease Not Available
    Gene Ensembl ENSG00000175206
    Target Classification Not Available

    The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015]



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