Human SLC39A14/cig19/HMNDYT2 ORF/cDNA clone-Lentivirus plasmid (NM_001351658)

Cat. No.: pGMLP001054
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SLC39A14/cig19/HMNDYT2 Lentiviral expression plasmid for SLC39A14 lentivirus packaging, SLC39A14 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001054
Gene Name SLC39A14
Accession Number NM_001351658
Gene ID 23516
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1509 bp
Gene Alias cig19,HMNDYT2,LZT-Hs4,NET34,ZIP14
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCATCCTTTCAGGGTTTATTCAGTCACCATGAAGCTGCTGCTGCTGCACCCGGCCTTCCAGAGCTGCCTCCTGCTGACCCTGCTTGGCTTATGGAGAACCACCCCTGAGGCTCACGCTTCATCCCTGGGTGCACCAGCTATCAGCGCTGCCTCCTTCCTGCAGGATCTAATACATCGGTATGGCGAGGGTGACAGCCTCACTCTGCAGCAGCTGAAGGCCCTACTCAACCACCTGGATGTGGGAGTGGGCCGGGGTAATGTCACCCAGCACGTGCAAGGACACAGGAACCTCTCCACGTGCTTTAGTTCTGGAGACCTCTTCACTGCCCACAATTTCAGCGAGCAGTCGCGGATTGGGAGCAGCGAGCTCCAGGAGTTCTGCCCCACCATCCTCCAGCAGCTGGATTCCCGGGCCTGCACCTCGGAGAACCAGGAAAACGAGGAGAATGAGCAGACGGAGGAGGGGCGGCCAAGCGCTGTTGAAGTGTGGGGATACGGTCTCCTCTGTGTGACCGTCATCTCCCTCTGCTCCCTCCTGGGGGCCAGCGTGGTGCCCTTCATGAAGAAGACCTTTTACAAGAGGCTGCTGCTCTACTTCATAGCTCTGGCGATTGGAACCCTCTACTCCAACGCCCTCTTCCAGCTCATCCCGGAGGCATTTGGTTTCAACCCTCTGGAAGATTATTATGTCTCCAAGTCTGCAGTGGTGTTTGGGGGCTTTTATCTTTTCTTTTTCACAGAGAAGATCTTGAAGATTCTTCTTAAGCAGAAAAATGAGCATCATCATGGACACAGCCATTATGCCTCTGAGTCGCTTCCCTCCAAGAAGGACCAGGAGGAGGGGGTGATGGAGAAGCTGCAGAACGGGGACCTGGACCACATGATTCCTCAGCACTGCAGCAGTGAGCTGGACGGCAAGGCGCCCATGGTGGACGAGAAGGTCATTGTGGGCTCGCTCTCTGTGCAGGACCTGCAGGCTTCCCAGAGTGCTTGCTACTGGCTGAAAGGTGTCCGCTACTCTGATATCGGCACTCTGGCCTGGATGATCACTCTGAGCGACGGCCTCCATAATTTCATCGATGGCCTGGCCATCGGTGCTTCCTTCACTGTGTCAGTTTTCCAAGGCATCAGCACCTCGGTGGCCATCCTCTGTGAGGAGTTCCCACATGAGCTAGGAGACTTTGTCATCCTGCTCAACGCTGGGATGAGCATCCAACAAGCTCTCTTCTTCAACTTCCTTTCTGCCTGCTGCTGCTACCTGGGTCTGGCCTTTGGCATCCTGGCCGGCAGCCACTTCTCTGCCAACTGGATTTTTGCGCTAGCTGGAGGAATGTTCTTGTATATTTCTCTGGCTGATATGTTCCCTGAGATGAATGAGGTCTGTCAAGAGGATGAAAGGAAGGGCAGCATCTTGATTCCATTTATCATCCAGAACCTGGGCCTCCTGACTGGATTCACCATCATGGTGGTCCTCACCATGTATTCAGGACAGATCCAGATTGGGTAG
ORF Protein Sequence MHPFRVYSVTMKLLLLHPAFQSCLLLTLLGLWRTTPEAHASSLGAPAISAASFLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLSTCFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAGSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQIQIG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1615-Ab Anti-S39AE/ SLC39A14/ HCIN monoclonal antibody
    Target Antigen GM-Tg-g-MP1615-Ag SLC39A14 VLP (virus-like particle)
    ORF Viral Vector pGMLP001054 Human SLC39A14 Lentivirus plasmid
    ORF Viral Vector vGMLP001054 Human SLC39A14 Lentivirus particle


    Target information

    Target ID GM-MP1615
    Target Name SLC39A14
    Gene ID 23516, 213053, 716112, 306009, 101087988, 486124, 515437
    Gene Symbol and Synonyms cig19,FAD-123,fad123,HCIN,HMNDYT2,LZT-Hs4,NET34,SLC39A14,ZIP-14,ZIP14
    Uniprot Accession Q15043
    Uniprot Entry Name S39AE_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000104635
    Target Classification Not Available

    This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.