Human EDAR/DL/ECTD10A ORF/cDNA clone-Lentivirus plasmid (NM_022336)

Cat. No.: pGMLP001634
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human EDAR/DL/ECTD10A Lentiviral expression plasmid for EDAR lentivirus packaging, EDAR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001634
Gene Name EDAR
Accession Number NM_022336
Gene ID 10913
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1347 bp
Gene Alias DL,ECTD10A,ECTD10B,ED1R,ED3,ED5,EDA-A1R,EDA1R,EDA3,HRM1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCCATGTGGGGGACTGCACGCAGACGCCCTGGCTCCCCGTCCTGGTGGTGTCTCTGATGTGCTCAGCCCGAGCGGAATACTCAAACTGCGGTGAGAACGAGTACTACAACCAGACTACGGGGCTGTGCCAGGAGTGCCCCCCGTGTGGGCCGGGAGAGGAGCCCTACCTGTCCTGTGGCTACGGCACCAAAGACGAGGACTACGGCTGCGTCCCCTGCCCGGCGGAGAAGTTTTCCAAAGGAGGCTACCAGATATGCAGGCGTCACAAAGACTGTGAGGGCTTCTTCCGGGCCACCGTGCTGACACCAGGGGACATGGAGAATGACGCTGAGTGTGGCCCTTGCCTCCCTGGCTACTACATGCTGGAGAACAGACCGAGGAACATCTATGGCATGGTCTGCTACTCCTGCCTCCTGGCACCCCCCAACACCAAGGAATGTGTGGGAGCCACTTCAGGAGCTTCTGCCAACTTCCCTGGCACCTCGGGCAGCAGCACCCTGTCTCCCTTCCAGCACGCCCACAAAGAACTCTCAGGCCAAGGACACCTGGCCACTGCCCTGATCATTGCAATGTCCACCATCTTCATCATGGCCATCGCCATCGTCCTCATCATCATGTTCTACATCCTGAAGACAAAGCCCTCTGCCCCAGCCTGTTGCACCAGCCACCCGGGGAAGAGCGTGGAGGCCCAAGTGAGCAAGGACGAGGAGAAGAAAGAGGCCCCAGACAACGTGGTGATGTTCTCCGAGAAGGATGAATTTGAGAAGCTGACAGCAACTCCAGCAAAGCCCACCAAGAGCGAGAACGATGCCTCATCCGAGAATGAGCAGCTGCTGAGCCGGAGCGTCGACAGTGATGAGGAGCCCGCCCCTGACAAGCAGGGCTCCCCGGAGCTGTGCCTGCTGTCGCTGGTTCACCTGGCCAGGGAGAAGTCTGCCACCAGCAACAAGTCAGCCGGGATTCAAAGCCGGAGGAAAAAGATCCTCGATGTGTATGCCAACGTGTGTGGAGTCGTGGAAGGTCTTAGCCCCACGGAGCTGCCATTTGATTGCCTCGAGAAGACTAGCCGAATGCTCAGCTCCACGTACAACTCTGAGAAGGCTGTTGTGAAAACGTGGCGCCACCTCGCCGAGAGCTTCGGCCTGAAGAGGGATGAGATTGGGGGCATGACAGACGGCATGCAACTCTTTGACCGCATCAGCACGGCAGGCTACAGCATCCCTGAGCTACTCACAAAACTGGTGCAGATTGAGCGGCTGGATGCTGTGGAGTCCTTGTGTGCAGACATACTGGAGTGGGCGGGGGTTGTGCCACCTGCCTCCCAGCCACATGCTGCATCCTGA
ORF Protein Sequence MAHVGDCTQTPWLPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCVPCPAEKFSKGGYQICRRHKDCEGFFRATVLTPGDMENDAECGPCLPGYYMLENRPRNIYGMVCYSCLLAPPNTKECVGATSGASANFPGTSGSSTLSPFQHAHKELSGQGHLATALIIAMSTIFIMAIAIVLIIMFYILKTKPSAPACCTSHPGKSVEAQVSKDEEKKEAPDNVVMFSEKDEFEKLTATPAKPTKSENDASSENEQLLSRSVDSDEEPAPDKQGSPELCLLSLVHLAREKSATSNKSAGIQSRRKKILDVYANVCGVVEGLSPTELPFDCLEKTSRMLSSTYNSEKAVVKTWRHLAESFGLKRDEIGGMTDGMQLFDRISTAGYSIPELLTKLVQIERLDAVESLCADILEWAGVVPPASQPHAAS

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0391-Ab Anti-EDAR/ DL/ ECTD10A monoclonal antibody
    Target Antigen GM-Tg-g-MP0391-Ag EDAR VLP (virus-like particle)
    ORF Viral Vector pGMLP001634 Human EDAR Lentivirus plasmid
    ORF Viral Vector vGMLP001634 Human EDAR Lentivirus particle


    Target information

    Target ID GM-MP0391
    Target Name EDAR
    Gene ID 10913, 13608, 695059, 365581, 101096644, 481305, 613947, 100060614
    Gene Symbol and Synonyms DL,ECTD10A,ECTD10B,ED1R,ED3,ED5,EDA-A1R,EDA1R,EDA3,EDAR,HRM1,RGD1561714
    Uniprot Accession Q9UNE0
    Uniprot Entry Name EDAR_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000135960
    Target Classification Not Available

    This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]



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