Human GP5/CD42d/GPV ORF/cDNA clone-Lentivirus plasmid (NM_004488)

Cat. No.: pGMLP001777
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human GP5/CD42d/GPV Lentiviral expression plasmid for GP5 lentivirus packaging, GP5 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001777
Gene Name GP5
Accession Number NM_004488
Gene ID 2814
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1683 bp
Gene Alias CD42d,GPV
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCTGAGGGGGACTCTACTGTGCGCGGTGCTCGGGCTTCTGCGCGCCCAGCCCTTCCCCTGTCCGCCAGCTTGCAAGTGTGTCTTCCGGGACGCCGCGCAGTGCTCGGGGGGCGACGTGGCGCGCATCTCCGCGCTAGGCCTGCCCACCAACCTCACGCACATCCTGCTCTTCGGAATGGGCCGCGGCGTCCTGCAGAGCCAGAGCTTCAGCGGCATGACCGTCCTGCAGCGCCTCATGATCTCCGACAGCCACATTTCCGCCGTTGCCCCCGGCACCTTCAGTGACCTGATAAAACTGAAAACCCTGAGGCTGTCGCGCAACAAAATCACGCATCTTCCAGGTGCGCTGCTGGATAAGATGGTGCTCCTGGAGCAGTTGTTTTTGGACCACAATGCGCTAAGGGGCATTGACCAAAACATGTTTCAGAAACTGGTTAACCTGCAGGAGCTCGCTCTGAACCAGAATCAGCTCGATTTCCTTCCTGCCAGTCTCTTCACGAATCTGGAGAACCTGAAGTTGTTGGATTTATCGGGAAACAACCTGACCCACCTGCCCAAGGGGTTGCTTGGAGCACAGGCTAAGCTCGAGAGACTTCTGCTCCACTCGAACCGCCTTGTGTCTCTGGATTCGGGGCTGTTGAACAGCCTGGGCGCCCTGACGGAGCTGCAGTTCCACCGAAATCACATCCGTTCCATCGCACCCGGGGCCTTCGACCGGCTCCCAAACCTCAGTTCTTTGACGCTTTCGAGAAACCACCTTGCGTTTCTCCCCTCTGCGCTCTTTCTTCATTCGCACAATCTGACTCTGTTGACTCTGTTCGAGAACCCGCTGGCAGAGCTCCCGGGGGTGCTCTTCGGGGAGATGGGGGGCCTGCAGGAGCTGTGGCTGAACCGCACCCAGCTGCGCACCCTGCCCGCCGCCGCCTTCCGCAACCTGAGCCGCCTGCGGTACTTAGGGGTGACTCTGAGCCCGCGGCTGAGCGCGCTTCCGCAGGGCGCCTTCCAGGGCCTTGGCGAGCTCCAGGTGCTCGCCCTGCACTCCAACGGCCTGACCGCCCTCCCCGACGGCTTGCTGCGCGGCCTCGGCAAGCTGCGCCAGGTGTCCCTGCGCCGCAACAGGCTGCGCGCCCTGCCCCGTGCCCTCTTCCGCAATCTCAGCAGCCTGGAGAGCGTCCAGCTCGACCACAACCAGCTGGAGACCCTGCCTGGCGACGTGTTTGGGGCTCTGCCCCGGCTGACGGAGGTCCTGTTGGGGCACAACTCCTGGCGCTGCGACTGTGGCCTGGGGCCCTTCCTGGGGTGGCTGCGGCAGCACCTAGGCCTCGTGGGCGGGGAAGAGCCCCCACGGTGCGCAGGCCCTGGGGCGCACGCCGGCCTGCCGCTCTGGGCCCTGCCGGGGGGTGACGCGGAGTGCCCGGGCCCCCGGGGCCCGCCTCCCCGCCCCGCTGCGGACAGCTCCTCGGAAGCCCCTGTCCACCCAGCCTTGGCTCCCAACAGCTCAGAACCCTGGGTGTGGGCCCAGCCGGTGACCACGGGCAAAGGTCAAGATCATAGTCCGTTCTGGGGGTTTTATTTTCTGCTTTTAGCTGTTCAGGCCATGATCACCGTGATCATCGTGTTTGCTATGATTAAAATTGGCCAACTCTTTCGAAAATTAATCAGAGAGAGAGCCCTTGGGTAA
ORF Protein Sequence MLRGTLLCAVLGLLRAQPFPCPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAECPGPRGPPPRPAADSSSEAPVHPALAPNSSEPWVWAQPVTTGKGQDHSPFWGFYFLLLAVQAMITVIIVFAMIKIGQLFRKLIRERALG

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0488-Ab Anti-GPV/ GP5/ CD42d monoclonal antibody
    Target Antigen GM-Tg-g-MP0488-Ag GP5 VLP (virus-like particle)
    ORF Viral Vector pGMLP001777 Human GP5 Lentivirus plasmid
    ORF Viral Vector vGMLP001777 Human GP5 Lentivirus particle


    Target information

    Target ID GM-MP0488
    Target Name GP5
    Gene ID 2814, 14729, 707776, 25259, 101090457, 522692, 100060025
    Gene Symbol and Synonyms CD42d,GP5,GPV,PLGPV
    Uniprot Accession P40197
    Uniprot Entry Name GPV_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000178732
    Target Classification Not Available

    Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]



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