Human ZP4/ZBP/Zp-4 ORF/cDNA clone-Lentivirus plasmid (NM_021186)

Cat. No.: pGMLP001807
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human ZP4/ZBP/Zp-4 Lentiviral expression plasmid for ZP4 lentivirus packaging, ZP4 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLP001807
Gene Name ZP4
Accession Number NM_021186
Gene ID 57829
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1623 bp
Gene Alias ZBP,Zp-4,ZP1,ZPB
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTGGCTGCTGCGGTGCGTTTTGCTGTGTGTTTCATTATCTCTTGCTGTGAGTGGCCAGCATAAGCCTGAGGCACCAGATTATTCCAGTGTGCTCCACTGTGGGCCGTGGAGCTTCCAGTTTGCTGTAAACCTCAACCAGGAGGCAACGTCTCCTCCTGTACTAATAGCTTGGGACAACCAAGGGCTGCTGCACGAGCTGCAGAATGACTCCGACTGTGGCACCTGGATAAGAAAAGGTCCAGGCAGCTCCGTGGTGTTGGAGGCAACCTATAGCAGCTGCTATGTCACTGAGTGGGACTCCCACTACATCATGCCAGTTGGAGTTGAAGGAGCAGGCGCGGCTGAACACAAGGTGGTTACAGAGAGGAAGCTGCTCAAGTGTCCTATGGATCTTCTAGCCCGAGATGCTCCAGATACTGACTGGTGTGACTCCATCCCAGCACGGGACAGACTGCCATGTGCACCTTCACCCATCTCTCGAGGAGACTGTGAAGGGCTAGGCTGTTGTTATAGCTCTGAAGAGGTGAATTCCTGCTACTATGGAAACACTGTGACCTTGCATTGTACCCGAGAGGGCCATTTCTCTATTGCTGTGTCTCGGAACGTGACCTCGCCACCACTGCTCTTGGATTCTGTGCGCTTGGCCCTTAGGAATGACAGTGCGTGTAACCCTGTGATGGCAACACAAGCTTTTGTTCTGTTCCAGTTTCCATTTACTTCCTGTGGCACCACAAGACAGATCACTGGAGACCGAGCAGTATATGAAAATGAACTGGTGGCAACTAGGGATGTGAAAAATGGGAGCCGTGGCTCTGTCACTCGTGACAGCATCTTCAGGCTCCATGTCAGCTGCAGCTACTCAGTAAGTAGCAACTCTCTCCCAATCAATGTCCAGGTTTTCACTCTCCCACCACCCTTTCCTGAGACCCAGCCTGGACCCCTCACTCTGGAACTTCAGATTGCCAAAGATAAAAACTATGGCTCTTACTACGGTGTTGGTGACTACCCAGTGGTGAAGTTGCTTCGGGATCCCATTTACGTGGAGGTCTCCATCCTTCACAGAACAGACCCCTACCTGGGGCTGCTCCTACAACAGTGTTGGGCAACACCCAGCACTGACCCCCTGAGTCAGCCACAGTGGCCCATCCTGGTAAAGGGCTGCCCCTACATTGGAGACAACTATCAGACCCAGCTGATCCCTGTCCAGAAAGCCTTGGATCTTCCATTTCCCTCTCACCACCAGCGCTTCAGCATCTTCACCTTCAGCTTTGTGAACCCTACAGTGGAGAAACAGGCCCTCAGGGGACCGGTGCATCTGCACTGCAGCGTGTCAGTCTGCCAGCCTGCTGAGACACCATCCTGTGTGGTGACCTGTCCTGATCTCAGTCGAAGAAGAAATTTTGACAACAGTTCTCAGAACACTACTGCTAGTGTTTCTAGCAAAGGCCCCATGATTCTACTCCAAGCCACTAAGGACCCTCCAGAAAAGCTCCGTGTTCCTGTAGACTCGAAAGTTCTGTGGGTGGCAGGCCTTTCTGGGACCTTAATCCTTGGAGCCTTGTTAGTATCCTACTTGGCTGTCAAGAAACAGAAGAGTTGCCCAGACCAAATGTGTCAATAA
ORF Protein Sequence MWLLRCVLLCVSLSLAVSGQHKPEAPDYSSVLHCGPWSFQFAVNLNQEATSPPVLIAWDNQGLLHELQNDSDCGTWIRKGPGSSVVLEATYSSCYVTEWDSHYIMPVGVEGAGAAEHKVVTERKLLKCPMDLLARDAPDTDWCDSIPARDRLPCAPSPISRGDCEGLGCCYSSEEVNSCYYGNTVTLHCTREGHFSIAVSRNVTSPPLLLDSVRLALRNDSACNPVMATQAFVLFQFPFTSCGTTRQITGDRAVYENELVATRDVKNGSRGSVTRDSIFRLHVSCSYSVSSNSLPINVQVFTLPPPFPETQPGPLTLELQIAKDKNYGSYYGVGDYPVVKLLRDPIYVEVSILHRTDPYLGLLLQQCWATPSTDPLSQPQWPILVKGCPYIGDNYQTQLIPVQKALDLPFPSHHQRFSIFTFSFVNPTVEKQALRGPVHLHCSVSVCQPAETPSCVVTCPDLSRRRNFDNSSQNTTASVSSKGPMILLQATKDPPEKLRVPVDSKVLWVAGLSGTLILGALLVSYLAVKKQKSCPDQMCQ

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1966-Ab Anti-ZP4/ ZBP/ ZP1 monoclonal antibody
    Target Antigen GM-Tg-g-MP1966-Ag ZP4 VLP (virus-like particle)
    ORF Viral Vector pGMLP001807 Human ZP4 Lentivirus plasmid
    ORF Viral Vector vGMLP001807 Human ZP4 Lentivirus particle


    Target information

    Target ID GM-MP1966
    Target Name ZP4
    Gene ID 57829, 709637, 282833, 493791, 442977, 280965, 100057402
    Gene Symbol and Synonyms TAC4,ZBP,Zp-4,ZP1,ZP1B,ZP4,ZPB,ZPB2
    Uniprot Accession Q12836
    Uniprot Entry Name ZP4_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000116996
    Target Classification Not Available

    The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq, Jul 2008]



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