Human LAMTOR1/C11orf59/p18 ORF/cDNA clone-Lentivirus plasmid (NM_017907)

Cat. No.: pGMLP002527
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human LAMTOR1/C11orf59/p18 Lentiviral expression plasmid for LAMTOR1 lentivirus packaging, LAMTOR1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP002527
Gene Name LAMTOR1
Accession Number NM_017907
Gene ID 55004
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 486 bp
Gene Alias C11orf59,p18,p27RF-Rho,PDRO,Ragulator1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGGGTGCTGCTACAGCAGCGAGAACGAGGACTCGGACCAGGACCGAGAGGAGCGGAAGCTGCTGCTGGACCCTAGCAGCCCCCCTACCAAAGCTCTCAATGGAGCCGAGCCCAACTACCACAGCCTGCCTTCCGCTCGCACTGATGAGCAGGCCCTGCTCTCTTCCATCCTTGCCAAGACAGCCAGCAACATCATTGATGTGTCTGCTGCAGACTCACAGGGCATGGAGCAGCATGAGTACATGGACCGTGCCAGGCAGTACAGCACCCGCTTGGCTGTGCTGAGCAGCAGCCTGACCCATTGGAAGAAGCTGCCACCGCTGCCGTCTCTTACCAGCCAGCCCCACCAAGTGCTGGCCAGTGAGCCCATCCCGTTCTCTGATTTGCAGCAGGTCTCCAGGATAGCTGCTTATGCCTACAGTGCACTTTCTCAGATCCGTGTGGACGCAAAAGAGGAGCTGGTTGTACAGTTTGGGATCCCATGA
ORF Protein Sequence MGCCYSSENEDSDQDREERKLLLDPSSPPTKALNGAEPNYHSLPSARTDEQALLSSILAKTASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVVQFGIP

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP2181-Ab Anti-LTOR1/ LAMTOR1/ C11orf59 monoclonal antibody
    Target Antigen GM-Tg-g-MP2181-Ag LAMTOR1 VLP (virus-like particle)
    ORF Viral Vector pGMLP002527 Human LAMTOR1 Lentivirus plasmid
    ORF Viral Vector vGMLP002527 Human LAMTOR1 Lentivirus particle


    Target information

    Target ID GM-MP2181
    Target Name LAMTOR1
    Gene ID 55004, 66508, 718249, 308869, 101085237, 485211, 614849, 100052779
    Gene Symbol and Synonyms 2400001E08Rik,C11orf59,C15H11orf59,LAMTOR1,p18,p27RF-Rho,PDRO,Ragulator1
    Uniprot Accession Q6IAA8
    Uniprot Entry Name LTOR1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Malignant neoplasm of prostate
    Gene Ensembl ENSG00000149357
    Target Classification Not Available

    Enables GTPase binding activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TOR signaling; and regulation of cholesterol transport. Located in lysosome. Part of Ragulator complex. [provided by Alliance of Genome Resources, Apr 2022]



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