Human B4GALNT1/GALGT/GalNAc-T ORF/cDNA clone-Lentivirus plasmid (NM_001276469)

Cat. No.: pGMLP002718
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human B4GALNT1/GALGT/GalNAc-T Lentiviral expression plasmid for B4GALNT1 lentivirus packaging, B4GALNT1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product Description

Catalog ID pGMLP002718
Gene Name B4GALNT1
Accession Number NM_001276469
Gene ID 2583
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 987 bp
Gene Alias GALGT,GalNAc-T,GALNACT,SPG26
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTGGCTGGGCCGCCGGGCCCTGTGCGCTCTGGTCCTTCTGCTCGCCTGCGCCTCGCTGGGGCTCCTGTACGCGAGCACCCGGGACGCGCCCGGCCTCCGGCTACCTCTTGCGCCGTGGGCGCCCCCGCAAAGCCCCCGCAGGCCCGAGCTGCCAGATCTTGCTCCTGAGCCCCGCTACGCACACATCCCGGTCAGGATCAAGGAGCAAGTAGTGGGGCTGCTGGCTTGGAACAACTGCAGTTGTGAGTCCAGTGGGGGGGGCCTCCCCCTCCCCTTCCAGAAACAAGTCCGAGCTATTGACCTCACCAAGGCCTTTGACCCTGCAGAGCTGAGGGCTGCCTCTGCCACAAGAGAGCAGGAGTTCCAGGCCTTTCTGTCGAGGAGCCAGTCCCCAGCTGACCAGCTGCTCATAGCCCCTGCCAACTCCCCGCTCCAGTACCCCCTACAGGGTGTGGAAGTTCAGCCCCTCAGGAGCATCTTGGTGCCAGGGCTGAGCCTTCAGGCAGCTTCTGGTCAGGAGGTATACCAGGTGAACCTGACTGCCTCCCTAGGCACCTGGGACGTGGCAGGGGAAGTGACTGGAGTTACTCTCACTGGAGAGGGTCAGGCAGATCTCACCCTTGTCAGCCCAGGGCTGGACCAACTCAACAGGCAACTACAACTGGTCACTTACAGCAGCCGAAGCTACCAGACCAACACAGCAGACACAGGTGCAAGGCCTGGGTGGAGAGACGGGCAGGCTGGGCAAACAGAGAAGAACCAGAAAGGCTGGAGTGGGCAAATGGCAGAGGGCATGGGAGGCATCTGGGCTATGGCCAGAGCTGTCCAGCCACACAATGGGTGCTTCAACTGGACCAGCAGGGCCAGAGGGAGAAAGGGGGCCTTTGTTCATCTGGGGCTGGAGCAGGCCAGAGGGAAACCCGAGCCTTGGGTGTGTCTCCCCTTTAGGCCAACTGTGGGGGGCCCCAGGAAGAGACTTGTCTAA
ORF Protein Sequence MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAPEPRYAHIPVRIKEQVVGLLAWNNCSCESSGGGLPLPFQKQVRAIDLTKAFDPAELRAASATREQEFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTGARPGWRDGQAGQTEKNQKGWSGQMAEGMGGIWAMARAVQPHNGCFNWTSRARGRKGAFVHLGLEQARGKPEPWVCLPFRPTVGGPRKRLV

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0128-Ab Anti-B4GN1/ B4GALNT1/ GALGT monoclonal antibody
    Target Antigen GM-Tg-g-MP0128-Ag B4GALNT1 VLP (virus-like particle)
    ORF Viral Vector pGMLP002718 Human B4GALNT1 Lentivirus plasmid
    ORF Viral Vector vGMLP002718 Human B4GALNT1 Lentivirus particle


    Target information

    Target ID GM-MP0128
    Target Name B4GALNT1
    Gene ID 2583, 14421, 715317, 64828, 101082581, 481129, 520159, 100053616
    Gene Symbol and Synonyms 4933429D13Rik,B4GALNT1,Gal-NAc-T,GALGT,Galgt1,GalNAc-T,GALNACT,Ggm-2,Ggm2,SPG26
    Uniprot Accession Q00973
    Uniprot Entry Name B4GN1_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000135454
    Target Classification Not Available

    GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]



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